Possible Involvement of Partial Biotinidase Deficiency in Alopecia Areata
September 1996
in “
Journal of the European Academy of Dermatology and Venereology
”
TLDR Biotin supplements may help hair regrowth in some alopecia areata patients.
The study investigated the role of biotinidase deficiency in alopecia areata (AA) by measuring biotinidase activity in 19 patients compared to 19 controls. Before treatment, patients had significantly lower biotinidase activity than controls. After 40 days of biotin supplementation (20 mg/day), 12 patients showed clinical remission, with new hair growth observed. The study suggested evaluating biotinidase activity in AA patients and recommended biotin supplements as a potential treatment.
