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Some children in Malaysia with symptoms have either profound or partial biotinidase deficiency, and early testing and treatment are important.

The study found two new mutations in a Chinese patient with severe biotinidase deficiency.

Valproic acid treatment may cause temporary hair loss due to reduced zinc and biotinidase levels, which tend to normalize after 6 months.

Valproate can cause both hair loss and curly hair in bipolar disorder patients.

Valproic acid may cause hair loss by reducing biotinidase enzyme activity in rats.

Biotinidase deficiency has various symptoms and can be treated with biotin supplements.

Valproic acid does not change biotinidase enzyme activity in children's blood.

Biotin supplements did not significantly reduce hair loss in rats on valproic acid.

Biotin supplements increased biotin levels but did not significantly prevent hair loss in rats on valproic acid.

Children taking higher doses of valproic acid had lower biotinidase activity, which may lead to biotin deficiency, but biotin supplements could help.

Valproic acid and carbamazepine do not change biotin or biotinidase levels but may lower zinc levels, still within normal range.

Biotin supplements improved skin and hair problems in a girl with biotinidase deficiency.

Biotin and biotinidase are essential to prevent health issues, and deficiencies require lifelong supplementation.

Valproic acid treatment increases a specific acid in urine by blocking an enzyme, possibly causing skin rash and hair loss.

Biotin supplements are not proven to improve hair or nails and may interfere with medical tests.

Children with partial biotinidase deficiency are healthy at birth but may develop symptoms that improve with biotin therapy.

Valproic Acid helps regrow hair in mice and activates a hair growth marker in human cells.

Biotin deficiency is not a major cause of Telogen Effluvium hair loss.

Valproic acid helped hair growth in alopecia patient; more research needed.

Biotin supplementation during isotretinoin treatment for acne may help maintain skin hydration and improve hair growth.

Valproate can cause hair problems, but there are ways to manage them.

Biotin may effectively treat hair loss caused by valproate medication.

A rare genetic disease causes sparse hair and early blindness due to a gene mutation.

The study suggests that analyzing DNA can help treat hair loss, but more research is needed.

Old drugs like finasteride and spironolactone are being successfully used for hair loss and skin conditions, and many other drugs show promise for new uses in dermatology.

Biotin supplements may improve hair and nail growth in people with certain deficiencies or conditions, but there's not enough evidence to recommend it for healthy individuals.

Male mice are more susceptible to autism-like changes from valproic acid than female mice.

Biotin deficiency is not a major cause of hair loss in women, so biotin supplements are not likely to be an effective hair loss treatment.

Valproic acid increases hair count in men with hair loss.

Levetiracetam may cause hair loss, which can potentially reverse with lower doses or stopping the drug.