Thermal spring waters and their microbes could be good for skin health and treating some skin conditions in skincare products.
June 2023 in “International journal of molecular sciences” Heat stress changes goats' skin and hair at the microscopic level and affects their genes and skin bacteria.
September 2021 in “Medicina estética” Sabal serrulata and biomimetic peptides with microneedling reduced hair loss and improved hair thickness in men with balding.
[object Object] 82 citations,
August 2017 in “Cell Reports” An imbalanced gut and lack of biotin can cause hair loss in mice.
78 citations,
January 2017 in “Skin appendage disorders” Biotin supplements may improve hair and nail growth in people with certain deficiencies or conditions, but there's not enough evidence to recommend it for healthy individuals.
71 citations,
January 2016 in “International Journal of Trichology” Biotin deficiency is not a major cause of hair loss in women, so biotin supplements are not likely to be an effective hair loss treatment.
57 citations,
February 2018 in “Journal of the American Academy of Dermatology” Biotin supplements are not proven to improve hair or nails and may interfere with medical tests.
[object Object] 55 citations,
December 1987 in “Archives of Dermatology” Two enzyme defects in biotin metabolism cause severe skin, hair, and metabolic issues.
55 citations,
July 1983 in “Journal of the American Academy of Dermatology” Biotin supplements can effectively treat hair loss and skin issues in certain enzyme deficiencies.
53 citations,
March 2003 in “Journal of Investigative Dermatology” Human skin cells have a high-affinity system for biotin transport, crucial for skin health.
43 citations,
April 2005 in “The Journal of Dermatology” Biotin supplements improved skin and hair in a biotin-deficient infant on amino acid formula.
29 citations,
July 1996 in “Acta Paediatrica” Biotin should be added to Japanese amino acid formula to prevent deficiency.
24 citations,
May 2017 in “PubMed” Biotin supplements for hair improvement are popular without scientific proof of effectiveness.
22 citations,
September 2008 in “Brain & development” Biotin supplements increased biotin levels but did not significantly prevent hair loss in rats on valproic acid.
21 citations,
June 2011 in “Journal of child neurology” Valproic acid and carbamazepine do not change biotin or biotinidase levels but may lower zinc levels, still within normal range.
13 citations,
August 2020 in “Journal of Laparoendoscopic & Advanced Surgical Techniques” Biotin supplements are generally ineffective in preventing hair loss after sleeve gastrectomy.
13 citations,
January 2019 in “Journal of the American Academy of Dermatology” Most people using biotin don't see skin improvements, and it may affect lab tests, so doctors shouldn't suggest it without confirming a deficiency.
11 citations,
February 2019 in “Journal of Cosmetic Dermatology” Low zinc and biotin levels linked to male hair loss; supplements may help.
10 citations,
September 2013 in “Nutrition” The ketogenic diet can worsen biotin deficiency, suggesting a need for biotin supplements.
6 citations,
January 2016 in “Pediatrics international” Japanese infants fed hydrolysate formula may have low biotin levels.
5 citations,
March 2021 in “International Journal of Dermatology” Biotin supplementation during isotretinoin treatment for acne may help maintain skin hydration and improve hair growth.
5 citations,
October 2019 in “Giornale italiano di dermatologia e venereologia” Biotin supplements can improve certain skin disorders and hair loss when a deficiency is present.
5 citations,
May 2019 in “Cureus” Taking biotin supplements can cause incorrect thyroid test results, leading to wrong diagnoses.
5 citations,
August 2017 in “The Journal of Clinical Psychiatry” Biotin may effectively treat hair loss caused by valproate medication.
4 citations,
March 2021 in “Experimental dermatology” Minoxidil increases nail growth more than biotin.
4 citations,
August 2018 in “Journal of The American Academy of Dermatology” The authors agree that biotin may help certain hair disorders but lacks evidence for use in healthy people and call for more research.
4 citations,
January 2015 in “Journal of microbial & biochemical technology” Biotin helps regulate proteins in the blood, which may explain its role in hair growth.
3 citations,
January 2017 in “Journal of cosmetology & trichology” The food supplement with L-cystine, Serenoa repens extract, and biotin safely reduced hair loss and improved hair growth in men and women.
2 citations,
August 2020 in “JCRPE” A girl with Denys-Drash syndrome was misdiagnosed due to biotin affecting her hormone test results.
2 citations,
March 2020 in “PubMed” Biotin deficiency is not a major cause of Telogen Effluvium hair loss.