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In this animal study, the ketogenic diet was associated with more severe biotin deficiency in biotin-deficient mice, suggesting that biotin supplementation is important when following this diet.

In this animal study, serum biotin levels and clinical symptoms in gilts suggested that serum biotin could serve as a sensitive indicator of biotin deficiency, and a system to evaluate biotin status was proposed.

This study concluded that locally manufactured finasteride tablets are bioequivalent to imported ones based on pharmacokinetic profiles in male volunteers.

Method accurately measures finasteride in tablets using finasteride-BSA interaction.

This study used micro-segmental hair analysis to identify the day of drug intake and suggested differing uptake mechanisms for co-administered drugs based on their properties.

This study concluded that newborn screening for biotinidase deficiency effectively identified cases and likely prevented irreversible complications from the disorder in some infants.

This study in humans and pigs found that finasteride metabolism is significantly influenced by CYP3A4, with induced metabolism decreasing and inhibited metabolism increasing plasma exposure of the drug.

This study found that the expression of certain biomarkers, including HER-2 and oestrogen receptor alpha, in breast skin may be influenced by the presence of breast cancer, suggesting a systemic effect.

This study explored the use of multiphoton microscopy to monitor changes in tumors and surrounding tissues in breast cancer patients undergoing neoadjuvant chemotherapy, finding it may effectively detect treatment response at cellular levels without using exogenous contrast agents.

This study concluded that two exemestane preparations are bioequivalent, using a high-performance liquid chromatographic mass spectrometric method to measure concentrations in human plasma.

This case report describes a girl in China with biotinidase deficiency confirmed by genetic mutations, whose skin and hair symptoms improved with biotin therapy.

This study demonstrated that dyeing can enhance the absorption coefficient of hair follicle tissues for selective photodestruction within human skin and hair follicles.

This study concluded that albumin-bound testosterone is biologically important and significantly contributes to testosterone bioavailability in women receiving spironolactone.

This study reviewed evidence on the role of specific genes (FKBP12, SAMAHD1, TRF2, CD155, and GATA3) in predicting how breast cancer patients might respond to adjuvant chemotherapy, aiming to monitor these markers in blood or tissue samples.

This study suggests that biotin therapy may be beneficial for individuals with partial biotinidase deficiency, as some developed symptoms later, which resolved with treatment.

This study found that a combination of betulin and cytostatic Namitecan had a statistically significant synergistic effect on solid Ehrlich adenocarcinoma tumors in NMRI mice, and suggests a promising method for administering betulin in in vivo experiments despite its water insolubility.

In this study, a 54-year-old woman with short bowel syndrome developed biotin deficiency and associated symptoms while on home parenteral nutrition lacking biotin, which improved significantly after supplementation.

This study developed a model predicting uranium excretion in human hair from drinking water exposure, suggesting it is a viable indicator for assessing internal uranium burden.

This study investigated the effects of biotin deficiency and adequacy on cell proliferation and DNA synthesis in isolated mohair follicles, particularly focusing on the incorporation of [methyl-3 H]thymidine.

In this study, the researchers found that different CDK4/6 inhibitors used in treating HR+/HER2- advanced breast cancer have varying safety profiles and impacts on patient quality of life.

This study developed and validated a method using hair samples to simultaneously detect bisphenols and parabens, enabling the quantification of these endocrine disruptors in a hospital population’s hair.

In this study, dietary biotin supplementation showed no significant benefit on reproductive performance in sows or pre-weaning growth and mortality in piglets.

In this study, the authors observed that controlled microflora in gnotobionts leads to delayed maturation of T-dependent lymphocytes in the thymus, affecting cellular immunity reactions.

This study concluded that two different pharmaceutical formulations of finasteride were bioequivalent in terms of rate and extent of absorption based on pharmacokinetic evaluations in a randomized crossover study with 38 volunteers.

This review highlights the need for methodologies to understand and quantify drug penetration into hair follicles as significant drug pathways, noting this area lacks comprehensive articles and reports no new results.

This study found that human keratinocytes express a sodium-dependent multivitamin transporter for biotin, pantothenic acid, and lipoic acid, including a highly specific biotin transport component.

This study identifies comedonal or cystic fibrofolliculomas as novel diagnostic clues for earlier recognition of Birt-Hogg-Dube syndrome, potentially facilitating timely surveillance of associated systemic complications.