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Non-classical 21 hydroxylase deficiency is an underdiagnosed cause of female hair loss and polycystic ovarian syndrome.

These drugs cause hair growth without affecting testosterone or adrenal hormones.

The 2023 guideline advises a detailed approach for PCOS, focusing on early detection, lifestyle and medical treatments, and managing health risks.

Hirsutism is common body hair growth due to genetics and hormones, and while not a disease, it can be distressing; virilisation includes hirsutism with other male traits and needs medical attention.

XEDAR triggers a specific signaling pathway in cells.

Plasma is better than Ringer's lactate for hair graft survival and growth after transplantation.

The article concludes that better diagnosis and management of Polycystic Ovarian Syndrome are needed to improve women's health and prevent related diseases.

Women with PCOS in North China often have hirsutism and acne, with hirsutism linked to metabolic issues.

Minoxidil stops cells from making prostacyclin, which may help with hair growth. More research is needed.

Mutations in the CYP21A2 gene are not a major factor in causing PCOS.

The conclusion is that accurately identifying the cause of high androgen levels in women with PCOS is crucial and requires specific tests.

AMH levels can't reliably tell the difference between LOCAH and all types of PCOS in women with excessive hair growth.

Clinical signs of excess male hormones and actual hormone levels in the blood do not always match in women with polycystic ovary syndrome.

Different types of skin stem cells can change and adapt, which is important for developing new treatments.

Certain fats in the skin help control inflammation and health, and changing these fats through diet or supplements might treat skin inflammation.

Combining Minoxidil and Rosemary oil in liposomes improves Minoxidil's effectiveness and remains stable for 60 days.

Spironolactone may help treat excessive hair growth in girls, but more research is needed.

About 13% of women had idiopathic hirsutism and 8.5% had polycystic ovary syndrome in a group of Iranian women.

Hormones significantly affect women's sexual function, and more research is needed to improve treatments for sexual dysfunction with minimal side effects.

The TRPV3 gene mutation affects hair growth by keeping mice in the growth phase longer, which could help treat hair loss.

The Ysc84/SH3yl1 protein family is important for cell movement and the process of taking in materials by interacting with actin and cell membranes.

The document concludes that managing non-classical congenital adrenal hyperplasia in females requires personalized treatment, genetic counseling, and a team of specialists.

ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.

A protein called ectodysplasin-A2 increases a hair growth inhibitor in balding cells, which could be a target for hair loss treatment.

Rare adrenal cancers that secrete androgens or estrogens have a poor prognosis and are treated primarily with surgery.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

Nanotechnology could improve hair regrowth but faces challenges like complexity and safety concerns.

The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.

The review suggests a comprehensive approach to treat hirsutism, focusing on hair removal, medication, and managing emotional effects.