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The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Avicennia marina extract and avicequinone C can potentially promote hair growth and treat hair loss by interfering with hair loss mechanisms and boosting growth factors.

Women with androgenetic alopecia (hair loss) have normal prostate specific antigen levels but higher testosterone levels.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Women with PCOS should be screened for heart disease risk and manage their health to prevent it.

The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.

Hair and nail cells share similar proteins, indicating a common differentiation pathway.

The nanofibers with two growth factors improved wound healing by supporting structure, preventing infection, and aiding tissue growth.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.

The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

Stem cell-derived conditioned medium shows promise for treating various medical conditions but requires standardized production and further validation.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Apoptosis is essential for human skin development and forming a functional epidermis.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

PCOS is caused by both genetics and environmental factors like diet and obesity.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

About 7% to 15% of Iranian women have polycystic ovary syndrome, depending on the criteria used to diagnose it.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Finasteride effectively treats BPH, but needs more trials to understand potential.

Certain cells from hair follicles can create new hair and contribute to hair growth when implanted in mice.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.