39 citations,
September 2012 in “Human Reproduction” Certain genetic variations in the SHBG gene are linked to an increased or decreased risk of PCOS in Mediterranean women.
39 citations,
January 2012 in “Reproductive Biology and Endocrinology” About 8.5% of women in Salvador, Brazil, have Polycystic Ovary Syndrome.
38 citations,
June 2018 in “Archives of Toxicology” Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
36 citations,
January 2006 in “Veterinary Dermatology” Cyclosporin effectively and safely treated skin diseases in three pets with no side effects.
35 citations,
January 2014 in “Postepy Dermatologii I Alergologii” DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.
33 citations,
August 2018 in “Facial Plastic Surgery Clinics of North America” The document explains hair biology, the causes of hair loss, and reviews various hair loss treatments.
31 citations,
April 2016 in “Nature communications” Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.
31 citations,
December 2002 in “Biochimica et biophysica acta. G, General subjects/Biochimica et biophysica acta. General subjects (Online)” The research found two types of calcium in human hair, one that varies among individuals and another that is consistent across people.
30 citations,
January 2019 in “Clinical Endocrinology” The study concluded that both anti-Mullerian hormone and LH/FSH ratio are higher in women with PCOS and combining these markers with BMI could improve diagnosis accuracy.
30 citations,
April 2014 in “Seminars in Reproductive Medicine” Diagnosing PCOS in teenagers is hard because its symptoms often look like normal puberty, and there's a need for better diagnosis methods and agreement on criteria.
29 citations,
April 2019 in “BMJ. British medical journal” Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.
29 citations,
July 2012 in “Fertility and Sterility” Low and ultralow doses of flutamide can cause liver damage in young women with high androgen levels, regardless of dose or birth control use, with higher risk for those with higher BMI and liver enzyme levels before treatment.
29 citations,
December 2005 in “BioEssays” Wnt/ß-catenin signaling is crucial for regulating skin stem cells and hair growth, with the right levels and timing needed for proper function.
28 citations,
November 2019 in “Gene” The ITGB6 gene is important for tissue repair and hair growth, and mutations can lead to enamel defects and other health issues.
28 citations,
July 2015 in “American Journal of Clinical Dermatology” People with Lichen Planus, especially with mucosal involvement, are more likely to have Metabolic Syndrome, which increases their risk for heart disease and diabetes.
28 citations,
April 2014 in “Hormones” Higher androstenedione levels in women with PCOS are linked to more severe symptoms.
27 citations,
January 2012 in “Current Topics in Microbiology and Immunology” Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.
26 citations,
October 2007 in “Experimental Dermatology” L-Carnitine-L-tartrate may help hair grow and prevent hair loss.
25 citations,
April 2015 in “Current problems in dermatology” Hair regrowth slows with age and can be affected by treatments that change enzyme activity in the skin.
25 citations,
June 2014 in “Journal of Endocrinology/Journal of endocrinology” Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.
25 citations,
June 2012 in “Endocrine” PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.
25 citations,
March 2000 in “Journal of Endocrinological Investigation” Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.
23 citations,
February 2021 in “Journal of Endocrinological Investigation” Betacoronaviruses, like COVID-19, may cause hormone system dysfunction and affect disease susceptibility and severity.
22 citations,
July 2017 in “BMC complementary and alternative medicine” Natural remedies for hair and scalp issues are still widely used in Palestine.
22 citations,
January 2009 in “Medical mycology” A family got a fungal infection from a boy who had contact with rabbits, but they all recovered with treatment.
21 citations,
October 2014 in “Antimicrobial Agents and Chemotherapy” Finasteride effectively prevents biofilm formation and treats preformed biofilms, but requires high doses.
20 citations,
March 2017 in “Reproductive Biology and Endocrinology” Women with PCOS have higher 5α-reductase activity, which may be linked to insulin resistance.
20 citations,
June 2012 in “Human Reproduction” Women with polycystic ovarian syndrome are more likely to have cervical insufficiency, especially South Asian and Black women.
19 citations,
January 2015 in “Current problems in dermatology” Ultraviolet rays damage hair, smoking may cause hair loss, and good nutrition is important for hair health, but genetics mainly decide hair thickness.
19 citations,
December 2008 in “Medical Journal of Australia” Baldness does not affect vitamin D levels in men.