research Synaptic-Like Vesicles and Candidate Transduction Channels in Mechanosensory Terminals
SLVs help maintain muscle stretch sensitivity and could aid in treating hypertension and muscle spasticity.
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720-750 / 852 resultsresearch PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and Synthetic Compounds
Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
research Expression Profile Analysis of MicroRNAs During Hair Follicle Development in the Sheep Fetus
Ten miRNAs may play key roles in starting secondary hair follicle development in sheep foetuses.
research New Case of Trichorhinophalangeal Syndrome-Like Phenotype with a De Novo t(2;8)(p16.1;q23.3) Translocation Which Does Not Disrupt the TRPS1 Gene
A woman with a unique syndrome similar to TRPS has a genetic change near the TRPS1 gene, affecting its regulation.
research Self-Amplifying RNA Approach for Protein Replacement Therapy
Self-amplifying RNA could be a better option for protein replacement therapy with lower doses and lasting effects, but delivering it into cells is still challenging.
research Network-Based Approaches Reveal Potential Therapeutic Targets for Host-Directed Antileishmanial Therapy Driving Drug Repurposing
Researchers identified five new potential targets for leishmaniasis treatment, suggesting repurposing existing drugs could be effective.
research Classification Framework for Healthy Hair and Alopecia Areata: A Machine Learning Approach
Machine learning can accurately identify Alopecia Areata, aiding in early detection and treatment of this hair loss condition.
research Measuring Patient Quality of Life Following Treatment for Alopecia
Alopecia treatments improve life quality but side effects can lessen this benefit; better use of quality of life measures is needed.
research Estrogen Deprivation Effects of Endocrine Therapy in Breast Cancer Patients: Incidence, Management and Outcome
Managing side effects of endocrine therapy is crucial to improve adherence and survival in breast cancer patients.
research CSI on Steroids: Forensic DNA Phenotyping by Columbia Police Department
Forensic DNA phenotyping can help generate new leads in cold cases but faces accuracy, legal, and acceptance challenges.
research Baricitinib for the Treatment of Alopecia Areata
Baricitinib helps regrow hair in adults with severe alopecia better than a placebo and is approved for treatment, but long-term effects are still unknown.
research The Need for Speed and Efficiency: A Brief Review of Small Molecule Antivirals for COVID-19
Some small molecule antivirals show promise against COVID-19, but more research is needed to understand and improve them.
research The Gut Microbiome And Alopecia Areata: Implications For Early Diagnostic Biomarkers And Novel Therapies
Gut bacteria differences may help diagnose and treat Alopecia areata.
research Nanoemulgel: For Promising Topical and Systemic Delivery
Nanoemulgel is a better way to deliver drugs through the skin for various conditions.
research How to Read a Research Paper: A Critical Examination of Tamsulosin and Dementia Risk
Tamsulosin may slightly increase dementia risk compared to other treatments for enlarged prostate.
research Anti-Wrinkle Effect of Bone Morphogenetic Protein Receptor 1a Extracellular Domain (BMPR1a-ECD)
BMPR1a-ECD reduces wrinkles much more effectively than retinoic acid.
research Evo Devo of the Vertebrate Integument
The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.
research Anxiety, Depression, and Quality of Life in Children and Adults With Alopecia Areata: A Systematic Review and Meta-Analysis
People with alopecia areata are more likely to have anxiety and depression and a lower quality of life.
research Polyphenol-Mediated Biomimetic Mineralization of Sacrificial Metal-Organic Framework Nanoparticles for Wound Healing
New wound healing method using nanoparticles in a gel speeds up healing and reduces infection and inflammation.
research Dihydroartemisinin Attenuates Benign Prostatic Hyperplasia in Rats by Inhibiting Prostatic Epithelial Cell Proliferation
Dihydroartemisinin helps reduce prostate enlargement in rats by stopping the growth of prostate cells.
research Redefining the 'E' in FUE: Excision Equals Incision Plus Extraction
The document suggests changing "Follicular Unit Extraction" to "Follicular Unit Excision" to more accurately describe the surgical hair transplant procedure.
research Unusual Acute Lupus Hemophagocytic Syndrome – A Test of Diagnostic Criteria: A Case Report
The 2012 criteria are better for diagnosing atypical lupus cases.
research Cicatricial Alopecia Symposium 2011: Lipids, Inflammation, and Stem Cells
The symposium concluded that a specific lipid might cause hair loss, inflammation is a key factor, and stem cells in bald scalps aren't working right, suggesting new treatment targets.
research Platelet-Rich Plasma in Dermatology: Cellular and Molecular Mechanisms of Action
PRP therapy helps skin heal and improve by promoting cell growth and repair.
research Detecting Shortcut Learning for Fair Medical AI Using Shortcut Testing
The ShorT method can detect and help reduce bias in medical AI by identifying shortcut learning.
research Proteomics as a Tool to Improve Novel Insights into Skin Diseases: What We Know and Where We Should Be Going
Proteomics combined with other technologies can lead to a better understanding of skin diseases.
research A Potential Predictive Role of the Scalp Microbiome Profiling in Patients with Alopecia Areata: Staphylococcus Caprae, Corynebacterium, and Cutibacterium Species
People with severe hair loss (Alopecia Areata) have different scalp bacteria than healthy people, which might help predict the condition's progress.
research Intra-Host SARS-CoV-2 Single-Nucleotide Variants Emerged During the Early Stage of COVID-19 Pandemic Forecast Population Fixing Mutations
Some early COVID-19 mutations in patients predicted future common virus mutations.
research Administration of Nrf-2-Modified Hair-Follicle MSCs Ameliorates DSS-Induced Ulcerative Colitis in Rats
Nrf-2-modified stem cells from hair follicles significantly improve ulcerative colitis in rats.
research Why Odds Ratios Can Be Tricky Statistics
Odds Ratios can be misleading; it's better to also present risk and Relative Risks for clarity.