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The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Oral minoxidil promotes hair growth but may cause side effects; needs monitoring.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Antiandrogen treatments combined with oral contraceptives can help manage hair growth and hair loss in women with PCOS.

Certain drugs that block specific enzymes can help treat prostate diseases.

Non-binary transgender individuals need personalized hormonal treatments for better well-being and quality of life.

BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.

Anti-androgens, like finasteride, dutasteride, and spironolactone, may lessen the severity of COVID-19 in men, leading to fewer ICU admissions.

Rosemary leaf extract may be an effective natural treatment for hair growth and male pattern baldness.

Androgenetic alopecia linked to COVID-19 severity; drugs reducing androgen receptor activation may help.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

New compounds with carborane showed anti-androgen effects similar to flutamide.

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

Some plant-derived compounds may help with hormonal conditions, but more research is needed to confirm their effectiveness.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

Finasteride reduces prostate bleeding by affecting blood vessel growth.

Hormone treatments can help with women's skin and hair disorders, but they need careful monitoring and more research.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

Using finasteride with TIP extends time off period for prostate cancer patients.

Early adrenal gland maturation in young children can be normal, but other serious conditions should be ruled out first.

Menopause affects hair and skin; more research needed for treatment.

The document concludes that managing non-classical congenital adrenal hyperplasia in females requires personalized treatment, genetic counseling, and a team of specialists.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Topical minoxidil helps treat female pattern hair loss, but more research needed for other treatments.

Finasteride may cause mental and sexual side effects, with hand preference and sexual orientation possibly affecting severity.