5 citations
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November 2013 in “Case reports in dermatology” This case report details a 57-year-old woman with frontal fibrosing alopecia who developed hyperpigmentation after treatment with dutasteride and pimecrolimus, highlighting no previously reported hyperpigmentation association with this combination.
15 citations
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July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” In a C3H mouse model, this study found that topical retinoids can significantly alter hair-cycle dynamics by prolonging the anagen phase and shortening the telogen phase, a reaction connected to increased cellular retinoic acid-binding protein levels.
58 citations
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February 2016 in “Scientific reports” This study found that dual inhibition of BACE1 and BACE2 in mice affects melanosome maturation and causes dose-dependent hair depigmentation without altering retinal morphology.
31 citations
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January 2014 in “The Scientific World JOURNAL” This study found that the water extract of Eclipta prostrata L. may protect skin cells against UVB-induced damage, likely due to its antioxidant properties and absorption of UVA and UVB radiation.
April 2016 in “Journal of The American Academy of Dermatology” In this study, exposure to ARBs, ACE inhibitors, and thiazides was associated with an increased risk of various skin cancers, including melanoma and nonmelanoma types, highlighting potential clinical implications for antihypertensive treatment choices.
5 citations
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January 1993 in “PubMed” In this study, retinoic acid treatments induced glandular and feather formation in embryos by altering positional values and activating specific retinoic acid nuclear receptor gene expression.
November 2022 in “Journal of Investigative Dermatology” This study found that apocynin restored collagen production, reduced DNA damage and senescence, and protected skin stem cells from aging in UVB-exposed human keratinocytes.
9 citations
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January 2021 in “Mediators of Inflammation” In this study, 15d-PGJ2 administered in a topical cream inhibited oxidative and inflammatory skin changes caused by UVB radiation in hairless mice, suggesting it as a promising treatment approach.
11 citations
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January 2016 in “Evidence-based Complementary and Alternative Medicine” This study found that rice bran ash extract and orthosilicic acid both increased melanin synthesis and related protein expression in melanocytes, suggesting potential therapeutic use for melanin deficiency.
41 citations
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October 2019 in “Biomolecules” This review highlights the role of all-trans retinoic acid in regulating stem and progenitor cell proliferation and differentiation, suggesting its potential to enhance treatments in regenerative medicine and cancer.
June 2026 in “British Journal of Dermatology” In this case study, a woman with alopecia areata experienced significant hair regrowth after starting ritlecitinib but developed an acneiform eruption, leading to the discontinuation of the drug and subsequent hair loss relapse; the eruption suggests a treatment-limiting adverse effect of JAK inhibitors.
September 2025 in “Value in Health” 1 citations
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March 2003 in “Journal of Investigative Dermatology” Early sunburn treatment with certain inhibitors may reduce skin cancer risk.
6 citations
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February 2004 in “Clinical and Experimental Ophthalmology” This case report indicates that retinoblastoma can occur in a microphthalmic eye and recommends using multiple imaging techniques due to potential differences in calcification visibility.
2 citations
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January 2018 in “International Journal of Advanced Community Medicine” This study reported the formulation of a new cream combining niacinamide and retinol aimed at reducing hyperpigmentation and providing anti-aging and moisturizing effects. It found that the cream remained stable under various environmental conditions and did not cause skin irritation in patch tests.
1 citations
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January 2023 in “Research Square (Research Square)” In this report, a 61-year-old woman with vitiligo showed significant improvement after tofacitinib treatment but developed lung adenocarcinoma, highlighting potential cancer risks associated with JAK inhibitors.
September 2016 in “Journal of the Egyptian Women's Dermatologic Society (Print)” This article explores the interactions between retinoids and the immune system but reports no new clinical results related to their role in hair cycle control.
3 citations
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January 1996 in “Journal of Dermatological Treatment” In this study, twice daily application of 3 μg/g calcitriol ointment was reported to be safe, effective, and well tolerated for treating moderate to severe chronic plaque psoriasis on the face and surrounding areas.
15 citations
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January 2025 in “Journal of the European Academy of Dermatology and Venereology” Ritlecitinib is effective and safe for treating alopecia areata, promoting significant hair regrowth.
3 citations
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April 1977 in “PubMed” In this study, patients with varying severities of acne, seborrhoea, and hirsutism responded differently to Cyproteronacetate and Ethinyloestradiol treatment, with improvement rates dependent on symptom severity and treatment duration.
22 citations
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April 1985 in “Australasian Journal of Dermatology” This review discusses the uncommon but potentially serious cutaneous reactions to beta-adrenergic blockers and the uncertain pathogenesis, with no new clinical results reported.
November 2025 in “SKIN The Journal of Cutaneous Medicine” This study evaluated the long-term safety of ritlecitinib in adolescents with alopecia areata and found it to be well-tolerated without new safety concerns over approximately five years, with common adverse events including positive SARS-CoV-2 tests, acne, headache, and nasopharyngitis.
December 2025 in “Journal of the European Academy of Dermatology and Venereology” This source states that an image was mistakenly misused in the supplementary materials but clarifies that this does not impact the study's main findings. The authors have corrected the error for accuracy and transparency.
126 citations
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October 1983 in “Journal of The American Academy of Dermatology” This report verifies isotretinoin's significant efficacy in treating severe acne over the past year in the U.S., highlighting the need for careful patient selection and monitoring due to potential side effects.
July 2026 in “Journal of the American Academy of Dermatology” January 2026 in “Annals of Dermatology” In this study, 80% of pediatric patients with alopecia areata treated with calcipotriol/betamethasone ointment showed hair regrowth over 12 weeks, suggesting it may be an effective option, though 20% had no improvement or worsening symptoms.
48 citations
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June 2000 in “Japanese Journal of Cancer Research” This study found that dimethylarsinic acid significantly accelerates skin tumor development in hair follicle-targeted K6/ODC transgenic mice.
This report describes a case where a young woman developed Kerion Celsi, a fungal skin infection, potentially linked to the use of a tretinoin, minoxidil, and betamethasone valerate lotion.
66 citations
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July 2003 in “International Journal of Dermatology” This study found that betamethasone valerate foam was more effective and well-tolerated than betamethasone dipropionate lotion in treating mild-to-moderate alopecia areata, with higher hair regrowth rates observed.
1 citations
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June 2016 in “Annals of the rheumatic diseases” In this study, researchers found that retinoids might improve lupus nephritis resistant to conventional treatments, but the sample size was too small for significant results, and side effects were noted.