Hyperpigmentation Following Treatment of Frontal Fibrosing Alopecia

    November 2013 in “ Case reports in dermatology ”
    Irma Margarita Pérez-Rodríguez, Martha Elena García-Meléndez, Kristian Eichelmann, Osvaldo Vázquez‐Martínez, Jorge Ocampo‐Candiani
    TLDR A woman's skin darkened after using dutasteride and pimecrolimus for hair loss, but improved when she stopped the medications and protected her skin from light.
    A 57-year-old postmenopausal woman with frontal fibrosing alopecia (FFA) was treated with dutasteride and pimecrolimus, which initially improved her condition. However, she developed hyperpigmentation on her joints and face after 8 months. Discontinuation of the treatment and use of photoprotection led to an 80% improvement in hyperpigmentation after 5 months. This case highlighted a previously unreported side effect of hyperpigmentation associated with the combination of dutasteride and pimecrolimus, suggesting the need for further studies to evaluate this association.
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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Fibrosing alopecia in a pattern distribution

      in Research/Science  14 upvotes 1 year ago
      A user has been experiencing hair loss for 4 years, with treatments like minoxidil, finasteride, and various supplements proving ineffective. They were diagnosed with fibrosing alopecia in a pattern distribution, a condition that may require a combination of anti-inflammatory and hair growth treatments.

      community can someone help me identify these pls

      in Treatment 3 months ago
      The user is experiencing diffuse thinning and inflammation despite using 2.5mg dutasteride daily, ciclopirox, and ketoconazole shampoos. They are considering treatments like hydroxychloroquine and JAK inhibitors due to suspected scarring alopecia and have faced challenges in obtaining a scalp biopsy.

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