research Role of 5α-Reductase Inhibitors in Androgen-Stimulated Skin Disorders
5α-reductase inhibitors like finasteride and dutasteride can help treat skin disorders stimulated by androgens, such as hair loss and acne.
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research Regarding Prostate-Specific Antigen: Let's Not Shoot the Messenger
The drugs finasteride and dutasteride reduce low-grade prostate cancers but may double the risk of high-grade cancers.
research Homologous Recombination Induced by Doxazosin Mesylate and Saw Palmetto in the Drosophila Wing-Spot Test
Doxazosin mesylate and saw palmetto cause genetic changes in fruit flies.
research 5α-Reductase Inhibitors: The Finasteride Story
Finasteride safely treats enlarged prostate and male-pattern baldness.
research Doxazosin and Finasteride Alone or in Combination: The PREDICT Study
Doxazosin alone or combined with finasteride improves prostate symptoms better than finasteride alone, without extra benefits.
research Clinical Use of 5α-Reductase Inhibitors
Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.
research Effect of Finasteride and/or Terazosin on Serum PSA: Results of VA Cooperative Study #359
Finasteride reduces PSA levels, terazosin doesn't affect them, and tracking prostate cancer in patients taking finasteride could be difficult.
![The Synthesis of (−)-4-Methyl-8-Chloro-Trans-1,2,3,4,4a,5,6,10b-Octahydrobenzo-[f]-Quinolin-3-One-[3-14C] (LY300502-14C) via a Circuitous Route](/images/research/73bab8dc-bdf0-45e3-8ef7-73d0d4b93cb1/small/21074.jpg)
research The Synthesis of (−)-4-Methyl-8-Chloro-Trans-1,2,3,4,4a,5,6,10b-Octahydrobenzo-[f]-Quinolin-3-One-[3-14C] (LY300502-14C) via a Circuitous Route
Scientists made a carbon-14 labeled version of a drug with a 48% yield and over 99% purity.
research Scientific Evaluation of a Unani Pharmacopoeia-Based Formulation on BPH in Animal Model
The Unani Pharmacopoeia-Based Formulation significantly improved symptoms of enlarged prostate in rats.
research 5-Alpha Reductase Inhibitor Related Litigation: A Legal Database Review
Most legal cases about 5α-reductase inhibitors, drugs for hair loss and prostate issues, complain about side effects and delayed cancer diagnosis, with most lawsuits settled out of court.
research Sexual, Physical, And Overall Adverse Effects In Patients Treated With 5α-Reductase Inhibitors: A Systematic Review And Meta-Analysis
Medications for hair loss and prostate issues can significantly increase the risk of sexual side effects and other negative symptoms.
research Acute Gross Hematuria: Etiology and Management
Most cases of visible blood in urine resolve on their own, but severe cases may need treatment.
research Targeting a Fibrotic Bottleneck May Provide an Opening in the Treatment of LUTS
New treatments targeting fibrosis could improve urinary symptoms in BPH.
research Pharmacophore and Atom-Based 3D QSAR Studies on the Novel 5-Alpha-Reductase Inhibitors
The developed model can predict effective 5-alpha-reductase enzyme inhibitors.
research Prescribing to Save Patients Money: Ethical Considerations
Doctors should prescribe cheaper, off-label medication and teach patients how to use it to save money ethically.
research Effects of 5-Alpha Reductase Inhibitors
5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.
research Discriminating in Favor of or Against Men with Increased Risk of Finasteride-Related Side Effects?
Finasteride treats baldness but may cause lasting sexual side effects.
research Reversible Visual Loss Caused by Combination Therapy of Alfuzosin and Finasteride in a Patient with Uveitic Glaucoma
Taking alfuzosin and finasteride together caused temporary vision loss in a glaucoma patient, but switching to tamsulosin helped.
research Testosterone Metabolite Nonessential For Androgen Effects
The body's change of testosterone into DHT is not necessary for testosterone's muscle and sexual effects.
research Dutasteride: A Review of Its Use in the Management of Prostate Disorders
Dutasteride is effective for treating prostate enlargement and reducing related surgery risk, but is not approved for preventing prostate cancer.
research Effect of Finasteride on Prostate-Specific Antigen
Finasteride significantly reduces PSA levels in men, and doctors should adjust PSA readings for those taking the drug.
research Crystal Structure and Synthesis of 17α-Hexanoyloxy-16β-Methylpregna-4,6-Diene-3,20-Dione
A new compound that could treat various androgen-related conditions was created and analyzed.
research Clinical Utility of GnRH Analogues in Female Androgen Excess: Highlighting Diagnostic and Therapeutic Applications
GnRH analogues are effective for diagnosing and treating female androgen excess, offering a non-surgical option.
research Physicochemical Characterization of Chitosan-Decorated Finasteride Solid Lipid Nanoparticles for Skin Drug Delivery
Chitosan-decorated nanoparticles can improve skin delivery and reduce side effects of finasteride.
research Antiandrogenic Activity of Riboflavin 5′-Phosphate (FMN) in 22Rv1 and LNCaP Human Prostate Cancer Cell Lines
Riboflavin 5′-phosphate (FMN) shows potential for treating androgen-related conditions but may be limited in treating prostate cancer.
research Bee Venom: Effectiveness on Skin Varicosities and Dermatological Benefits
Bee venom can improve various skin conditions, including varicose veins and psoriasis, and has anti-aging benefits.
research Marijuana, Alcohol, Erectile Dysfunction, And Depression: Epidemiologic Correlations With Benign Prostatic Hyperplasia/Lower Urinary Tract Symptoms
Marijuana use is linked to higher chances of needing treatment for urinary symptoms in men over 40.
research Dermatological Findings in Multiple Sclerosis Patients in the Bolu Region
MS patients often have skin issues, so regular skin checks are important.
research Post-Finasteride Syndrome: A Review of Current Literature
Post-finasteride Syndrome causes lasting negative effects, but more research is needed for treatment and risk evaluation.
research Can Long-Term LUTS/BPH Pharmacological Treatment Alter the Outcomes of Surgical Intervention?
Long-term medication for enlarged prostate might not clearly affect the timing or outcomes of later surgery.