Marijuana, Alcohol, Erectile Dysfunction, And Depression: Epidemiologic Correlations With Benign Prostatic Hyperplasia/Lower Urinary Tract Symptoms

The study investigated the associations between marijuana (MJ) and alcohol (AL) use, along with other medical comorbidities, and the treatment of benign prostatic hyperplasia with lower urinary tract symptoms (BPH/LUTS) in men over 40. Data from nearly 2 million patients were analyzed, with 173,469 meeting the inclusion criteria. Results showed that MJ use, erectile dysfunction (ED), and depression were associated with an increased likelihood of being on LUTS medication, while AL use was associated with a decreased risk. Multivariable analysis confirmed that MJ use, ED, and depression were significant factors, whereas AL use had no significant association. The study highlighted MJ use as a newly described factor associated with LUTS, suggesting a need for further understanding of this relationship.