5 citations,
August 2013 in “InTech eBooks” KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.
43 citations,
March 2009 in “Journal of Cellular and Molecular Medicine” TGF-β2 plays a key role in human hair growth and development.
3 citations,
January 2021 in “Oxidative Medicine and Cellular Longevity” Nrf-2-modified stem cells from hair follicles significantly improve ulcerative colitis in rats.
8 citations,
October 2018 in “Applied sciences” Alginate spheres help maintain hair growth potential in human cells for hair loss treatment.
14 citations,
February 2021 in “Experimental Dermatology” Cannabinoid receptor-1 signaling is essential for the survival and growth of human hair follicle stem cells.
3 citations,
August 2014 in “Cellular reprogramming” Hair follicle stem cells need all reprogramming factors to become pluripotent.
3 citations,
January 2019 in “Advances in stem cells and their niches” Dermal papilla cells are key for hair growth and color, influencing hair type and size, and their interaction with stem cells could help treat hair loss and color disorders.
3 citations,
February 2022 in “Frontiers in Genetics” The LncRNA AC010789.1 slows down hair loss by promoting hair follicle growth and interacting with miR-21 and the Wnt/β-catenin pathway.
November 2023 in “International Journal of Medical Sciences” New regenerative medicine-based therapies for hair loss look promising but need more clinical validation.
421 citations,
April 2012 in “The New England Journal of Medicine” Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.
75 citations,
October 2016 in “Genes & Development” Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.
2 citations,
July 2022 in “Cell Regeneration” Understanding hair growth involves complex factors, and more research is needed to improve treatments for hair loss conditions.
46 citations,
June 2015 in “Journal of Investigative Dermatology” Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.
224 citations,
March 2006 in “Seminars in Cutaneous Medicine and Surgery” The document concludes that understanding hair follicle biology can lead to better hair loss treatments.
14 citations,
May 2017 in “InTech eBooks” Hair is important for protection, social interaction, and temperature control, and is made of a growth cycle-influenced follicle and a complex shaft.
1 citations,
January 2017 in “Springer eBooks” The document explains how hair follicles develop, their structure, and how they grow.
January 2018 in “Elsevier eBooks” The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.
1113 citations,
August 1999 in “The New England Journal of Medicine” Hair follicle biology advancements may lead to better hair growth disorder treatments.
23 citations,
December 2001 in “Lasers in Surgery and Medicine” Permanent hair removal is hard, but using longer laser pulses at lower power might improve results.
29 citations,
May 2020 in “npj Regenerative Medicine” Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.
6 citations,
April 2022 in “Journal of diabetes research” Type 2 diabetes slows down skin and hair renewal by blocking important stem cell activation in mice.
18 citations,
February 2022 in “Cell Death Discovery” ECM1-modified stem cells can effectively treat liver cirrhosis.
July 2023 in “The Egyptian Journal of Hospital Medicine ” Alopecia areata is a hair loss condition caused by immune factors and can be treated with JAK inhibitors.
139 citations,
July 1991 in “Journal of The American Academy of Dermatology” Understanding hair follicle anatomy helps diagnose hair disorders.
63 citations,
November 1999 in “British journal of dermatology/British journal of dermatology, Supplement” Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.
24 citations,
January 2008 in “KARGER eBooks” The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.
October 2018 in “Springer eBooks” The document concludes that various hair disorders have different treatments, including medication, surgery, and addressing underlying causes.
22 citations,
June 2002 in “Seminars in cutaneous medicine and surgery” Laser hair removal works well for people with dark hair and light skin, but it's less effective for light hair or dark skin; improvements are expected.
13 citations,
January 2010 in “Advances in Biochemical Engineering / Biotechnology” Understanding hair biology is key to developing better treatments for hair and scalp issues.
1 citations,
January 2019 in “Springer eBooks” Hidradenitis Suppurativa is a chronic skin condition best treated early with surgery for better outcomes and less recurrence.