January 2017 in “Enlighten: Publications (The University of Glasgow)” This study found that in mice with deregulated β-catenin and PTEN signaling, increased follicular hyperplasia and sebaceous gland changes occur, but typical papillomas do not develop, potentially due to p21 response and reduced stem cell markers.
January 2025 in “eScholarship@McGill (McGill)” In this study, loss of the Notch ligand Jag2 in mouse epidermal cells disrupted early differentiation and affected the structure and behavior of adjacent melanocytes, highlighting Jag2's role in epidermal differentiation and tissue homeostasis.
25 citations
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June 2022 in “Developmental cell” In this study, Hedgehog signaling in dermal papilla fibroblasts was found to accelerate hair growth and induce follicle multiplication in mice via the SCUBE3/TGF-β pathway, with some effects observed in human scalp hair follicles.
May 2018 in “Journal of Investigative Dermatology” Activating Wnt in skin cells controls the number of hair follicles by directing cell movement and fate.
17 citations
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May 2022 in “Cells and Development” April 2026 in “Chinese Chemical Letters”
January 2020 in “Journal of Entomology and Zoology Studies” This study found that canine hair follicle stem cells are located in the isthmus/bulge region of the hair follicle, surrounded by telocytes.
27 citations
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December 1997 in “Archives of Dermatological Research” This study observed that cultured dermal papilla cells showed distinct functional properties from dermal fibroblasts, including lower proliferation rates, higher adhesion to collagen type IV, and different cell-matrix interactions.
1 citations
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December 2018 in “Veterinary dermatology” This study documented that symmetrical, noninflammatory alopecia in schipperkes is associated with hormonal abnormalities and hair cycle arrest, resembling Alopecia X clinically and histologically.
19 citations
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June 2002 in “American Journal of Dermatopathology” This study found significant differences in bcl-2 expression between areas of the scalp affected and unaffected by androgenetic alopecia, suggesting a uniform follicle population or synchronized follicular cycling in affected areas.
October 2018 in “Deep Blue (University of Michigan)” This study found that matrix progenitor cell differentiation in hair growth has distinct early and late phases, and generated a mouse model to explore the hair follicle's role in harlequin ichthyosis.
4 citations
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January 2013 in “International Journal of Trichology” This study found that the distribution of desmogleins is associated with specific types of keratinization and hair anchorage, as well as hypotrichosis.
2 citations
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November 2023 in “Skin Research and Technology” This study found that RCM combined with dermoscopy can differentiate disease states between alopecia areata, tinea capitis, nevus sebaceous, and linear scleroderma of the scalp by identifying distinct dermal and follicular patterns.
November 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” In this study, researchers conducted additional IHC staining on equine skin sections and found that collagen type III primarily labels the extracellular matrix, while anti-PDGFR-antibody staining highlights cells with long-shaped processes mainly arranged around hair follicles.
June 2025 in “British Journal of Dermatology” In this study, researchers describe a rare case of trichoepitheliomas in a 7-year-old boy, characterized by multiple skin lesions in a Blaschko-linear pattern, hypothesizing it as a type 1 segmental mosaicism without detected CYLD gene mutations.
4 citations
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March 2024 in “Developmental Dynamics” In this study, researchers used conditional mouse models to show that inactivation of the Alx4 gene in specific cell lineages leads to craniofacial and limb defects without affecting postnatal survival, providing insights into Alx4's role in development and disease.
6 citations
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December 2014 in “Clinical and Experimental Dermatology” In this study, hair density and thickness in nonbalding scalp areas varied with the severity and BASP subtypes of androgenetic alopecia in East Asian men, showing notable decreases in some subtypes.
34 citations
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December 1995 in “Pediatric Dermatology” In this study, researchers reported a 0.11% occurrence of congenital triangular alopecia, recommending surgical treatment for women but not for men due to later potential development of androgenic alopecia.
12 citations
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March 2004 in “Journal of Investigative Dermatology” 32 citations
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November 2006 in “Veterinary dermatology” This review discusses the various forms of congenital alopecia in domestic animals and highlights the need for improved classification due to limited understanding and rarity; it reports no new clinical results.
11 citations
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September 2021 in “Skin Appendage Disorders” This study observed variability in hair density and types across different scalp areas in cadaver biopsies, providing reference values that could aid in diagnosing hair disorders in Asians.
44 citations
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October 1990 in “Archives of Dermatological Research” The connective tissue around hair follicles changes structure throughout the hair cycle.
September 2024 in “Indian Journal of Dermatology Venereology and Leprology”
1 citations
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July 2010 in “Dermatologic Surgery” This text resembles an instructional or informational template for journal subscribers and authors, not a research abstract reporting specific findings.
5 citations
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January 2022 in “Scientific reports” This study identified distinct gene expression programs in keratinocytes responsible for forming hard scales and soft interscale epidermis in chickens, revealing conserved differentiation genes similar to those in human skin.
11 citations
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June 2010 in “Medical Molecular Morphology”
April 2023 in “Journal of Investigative Dermatology” In this study using a mouse model of Pemphigus vulgaris, researchers found that loss of desmoglein 3 adhesion in hair follicle stem cells triggers a regenerative program restoring stem cell function, requiring Hedgehog pathway suppression.
14 citations
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January 1998 in “Dermatology” This study found evidence that polythelia pilosa, previously excluded from classification, should be reintroduced as it marks true aberrant mammary structures in men and hirsute women.
April 2016 in “Journal of the American Academy of Dermatology” A 4-year-old girl had a rare hair disorder affecting only part of her scalp.
7 citations
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April 1996 in “British Journal of Dermatology” This study found that intermediate filaments and matrix proteins in presumptive hair shaft cells are synthesized sequentially, identifying a new polypeptide component that changes during hair cell differentiation.