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The document discusses various diseases of the outer ear, categorized by symptoms like redness, crusts, bumps, pus-filled lesions, lumps, ulcers, and hair loss.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.

Activin increases skin tumor formation, skin Tregs help hair growth, lymph-node removal doesn't improve melanoma survival, cells can revert to stem cells in wound healing, and skin bacteria produce peptides that may treat infections.

Tofacitinib helped most patients with alopecia areata regrow hair and changes in immune cells were linked to the treatment's effectiveness.

Transplant patients on immunosuppressive medications have a higher risk of skin cancer, and managing this involves balancing medication with cancer risk.

Some patients developed skin inflammation after obesity surgery, and a medication called dapsone helped treat it.

Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.

A benign tumor developed at a girl's BCG vaccination site, not previously linked to the vaccine.

A kidney transplant patient on cyclosporin experienced unexpected severe hair loss, which improved with treatment adjustments.

Trichoblastomas in rabbits are linked to uncontrolled embryonic hair growth and have distinct histological features.

A man with a rare scalp cancer was successfully treated, highlighting the need for early management to prevent spread and complications.

Contact immunotherapy might help treat various skin conditions, but more research is needed to confirm its safety and effectiveness.

Science improves peace by advancing medical treatments, like laser therapies and non-invasive imaging.

COVID-19 can cause different skin symptoms that may help with early diagnosis and show how severe the disease is.

Scientists found a gene in mice that causes early hearing loss.

Lack of Ctip2 in skin cells delays wound healing and disrupts hair follicle stem cell markers in mice.

Current and future treatments for alopecia areata focus on immunosuppression, immunomodulation, and protecting hair follicles.

Neuregulin3 affects cell development in the skin and mammary glands.

The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.

Demodex mites rarely cause scalp infections leading to hair loss, but when they do, treatment is effective.

Hair follicle cells resist turning into skin cells.

GLI1 might protect against the start of skin cancer and is not linked to cancer severity.

Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.

Topical treatments can deliver active molecules to skin stem cells, potentially helping treat skin and hair disorders, including skin cancers and hair loss.

Careful histologic examination is crucial to differentiate types of bullous lesions in cutaneous lupus erythematosus.

Hair loss in a drug reaction case involved both a common shedding phase and an immune attack on hair follicle stem cells.

A woman had a unique skin growth with hair follicle, oil glands, fat cells, spindle cells, and nerve fibers.

Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.

The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."