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In this study, researchers observed that TLR3 and scavenger receptors play key roles in skin barrier repair following UVB damage, contributing to our understanding of cellular responses to skin injury.

This study found that bioconjugating 16-methylheptadecanoic acid to damaged human hair can mimic the protective function of the original 18-methyleicosanoic acid, effectively restoring both the hair's external structural integrity and its internal moisture balance.

This review discusses the roles of human tissue kallikreins in skin physiology and pathology and reports no new findings, emphasizing their potential involvement in various skin functions and conditions.

This study found significant changes in gene expression related to skin structure and signaling pathways in AEC syndrome skin, offering new insights into the syndrome's molecular underpinnings.

This study suggests that the Anetholea anisita extract improved scalp health by increasing specialized pro-resolving mediators and reducing pro-inflammatory markers, leading to decreased dandruff and enhanced hair brightness in dandruff sufferers.

This study found that actively targeted AN2728-loaded nanocarriers reduced inflammation and improved skin condition in a mouse model of psoriasiform inflammation compared to free drug and non-targeted nanoparticles.

This literature review examines current anti-aging therapies, focusing on innovative genetic cosmeceuticals enhanced by nanotechnology, which offer targeted and minimally invasive treatment options by effectively delivering anti-ageing genetic elements to skin cells and potentially improving skin health through reduced oxidative stress.

This article discusses the role of stratum corneum disruption in dandruff and suggests that treatments improving scalp barrier integrity along with antifungal activity may be beneficial; it reports no new research findings.

In this study assessing post-menopausal Asian women, distinct shifts in Malassezia species prevalence on the skin were linked to increased inflammation and impaired skin barrier function, potentially driving disorders like psoriasis and seborrheic dermatitis.

This study highlights that ZNF750, a zinc-finger transcription factor, is crucial for epidermal differentiation and barrier formation in skin by activating genes involved in lipid processing and stratum corneum development, and links ZNF750 sequence variations to skin inflammatory diseases like psoriasis.

This study found that sebaceous-gland-derived glycerol significantly contributes to stratum corneum hydration in mice with sebaceous gland deficiencies.

In this study, it was observed that NIPAL4 mutations linked to autosomal recessive congenital ichthyosis lead to abnormal skin barrier function due to cytotoxic effects disrupting lipid structure and organization, which topical treatments only partially ameliorated.

This review discusses recent advancements in nanotechnology for treating hypertrophic scarring and atopic dermatitis, highlighting the potential of nanotherapeutic platforms in enhancing therapeutic effects by modulating the skin's microenvironment.

This study examines the genetic underpinnings of chronic dermatological conditions like acne, androgenetic alopecia, and alopecia areata, concluding that a deep understanding of these mechanisms can advance patient-specific treatments and inform cosmetic practices related to skin and hair health.

This study presents a method for directly measuring the solubility of solid chemicals in the skin's stratum corneum under various humidity conditions, emphasizing its importance for dermal drug delivery and chemical safety assessments.

This review covers various disorders of cornification and their treatments, offering clinical insights but reporting no new research findings.

This review discusses the development, function, and complex roles of sebaceous glands in acne and suggests future acne treatments should target inflammation and lipid production; it reports no new clinical results.

This review discusses various nanoparticles used to enhance skin permeation and target delivery to skin organelles, but reports no new experimental results.

This review discusses the role of the enzyme Δ9-desaturase-1 in skin lipid regulation and whole-body energy balance in mice and reports no new experimental results.

The study concluded that fatty acid transport protein 4 in epidermal keratinocytes is crucial for maintaining normal skin structure, as its deficiency led to hyperkeratosis and epidermal barrier disruption in mice.

This review synthesizes current research on PPAR-γ signaling in hair follicle biology and its potential role in treating hair growth disorders like scarring alopecia and hirsutism, but reports no new clinical results.

In this study, the use of two emollients significantly reduced itching severity in individuals with xerotic eczema, starting 30 minutes post-application, and improved skin moisture and lipid content over 14 days, while demonstrating good tolerance with few adverse events.

This chapter discusses the structure and function of the skin, detailing its protective roles and the layers that comprise it, but reports no new research findings.

In this study, researchers found that cosmetic formulations containing guaraná extract effectively controlled oiliness in oily skin and hair by reducing sebaceous gland activity and lipid content without compromising skin barrier function, making them promising for managing excessive sebum production.

This review discusses various nanoparticles and nanoemulsions being investigated for transdermal drug delivery and reports no clinical results; it highlights potential applications in treating alopecia, wound healing, psoriasis, and melanoma.

This article reviews key questions in skin biology, particularly the mechanisms of hair follicle patterning and the role of stem cells in the epidermis, reporting no new results.

This review highlights recent findings on the importance of signalling pathways in sebaceous gland morphogenesis and differentiation, but reports no new clinical results.

This study found that the stratum corneum of scalp skin in humans has distinct functional characteristics compared to the facial skin and volar forearm, including higher hydration levels and intermediate epidermal turnover rates.

This review explores research on nanoformulations for enhancing the topical delivery of herbal medicines, noting potential benefits like improved bioavailability and sustained delivery, and emphasizes the need for safety and toxicity guidelines in developing these novel drug delivery systems.

This study found that mice lacking sPLA2-IIE had distinct skin abnormalities, particularly affecting hair follicles, highlighting the differing roles of sPLA2 isoforms in mouse skin.