In this study using a mouse model, researchers utilized single-cell RNA sequencing to create a comprehensive cellular atlas of infected versus uninfected wounds, revealing that Enterococcus faecalis infections lead to immunosuppressive changes in skin cells and disrupt normal wound healing processes.
1 citations
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February 2020 in “The Journal of clinical investigation/The journal of clinical investigation” This study elucidates a mechanism for acne-like skin toxicity caused by EGFR/MEK inhibitors, involving an interaction with skin bacteria to trigger inflammation, which supports existing antibiotic treatment practices.
January 2024 in “International Journal of Advanced Biochemistry Research” In this study investigating canine pyoderma, the researchers found that Staphylococcus species isolated from 57 dogs were most sensitive to the antibiotic Linezolid, with a 100% sensitivity rate, followed by other antibiotics like Doxycycline hydrochloride and Cefpodoxime.
October 2004 in “Emergency Medicine News” This article reviews the treatment and characteristics of skin infections like carbuncles and furuncles related to Staphylococcus aureus, but presents no new clinical findings.
3 citations
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January 2021 in “Molecular genetics & genomic medicine” In this study, novel mutations in the BTD gene were identified in a patient with profound biotinidase deficiency, highlighting the importance of biotinidase activity measurement and mutation analysis for early diagnosis.
July 2022 in “Journal of Investigative Dermatology” This study identified that bacterially-induced metabolic changes in keratinocytes enhance skin and hair follicle regeneration, suggesting that modifying skin microbiome interactions may improve wound healing.
April 2018 in “Journal of Investigative Dermatology” This study found that palmoplantar pustulosis patients exhibited oral dysbiosis, particularly among those with pustulotic arthro-osteosis, as compared to healthy controls.
June 2025 in “Indian Journal of Veterinary Medicine” In this case report, a persistent skin infection in a Bullykutta dog was resolved with a 10-day treatment regimen of Sulphamethoxazole, trimethoprim, omega fatty acids, and topical therapy after previous treatments failed.
December 2024 in “Buletin Veteriner Udayana” This case report from Darmasaba Village, Bali, identified Colisepticemia in a 27-day-old chicken, based on clinical signs, pathology, and laboratory tests, and highlighted the need for improved farm hygiene and sanitation to prevent disease spread.
2 citations
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September 2019 in “Serbian Journal of Dermatology and Venerology” In this study, a 63-year-old male with chronic acne necrotica achieved complete clinical remission using topical erythromycin and benzoyl peroxide.
July 2021 in “Journal of dermatology research and therapy” This article discusses the mechanisms by which Cutibacterium acnes contributes to acne vulgaris and mentions potential triggers like UV light and tobacco, but it reports no new clinical results.
8 citations
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August 2021 in “Aging” This animal study found that berberine may alleviate benign prostatic hyperplasia by reducing inflammation and oxidative stress through inhibition of the NF-κB signaling pathway.
June 2024 in “Current Developments in Nutrition” This study found that a nutritional intervention in dogs led to changes in skin microbiome and immune-related gene expression, with reduced levels of certain fungal pathogens and a potential alleviation of atopic dermatitis symptoms.
166 citations
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November 2008 in “Expert Review of Endocrinology & Metabolism” This review discusses biotin and biotinidase deficiencies, their symptoms, and methods of medical management, without presenting new clinical findings.
January 2026 in “Romanian Journal of Military Medicine” This study found that both Lactobacillus casei extract and Newcastle disease virus significantly reduced cell viability and induced apoptosis in human colorectal cancer cells, suggesting these agents could complement standard chemotherapy and radiotherapy after further clinical trials.
February 1994 in “Neuroscience letters” This review provides an overview of biotin's role in metabolism and the consequences of deficiency but reports no new clinical findings; it highlights that intestinal bacteria usually meet biotin needs.
11 citations
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October 2024 in “PLoS ONE” In this study, phage-containing hydrogels were shown to effectively treat wounds infected with E. faecalis by promoting wound healing through controlled phage release, suggesting potential to improve clinical outcomes for such infections.
January 2020 in “Korean Journal of Food Science and Technology” This study found that methanol extracts from four natural products inhibited the growth of Vibrio vulnificus in Luria-Bertani broth, seawater, and shellfish, while also protecting HeLa cells from its cytotoxic effects, suggesting their potential as safe antimicrobial agents.
February 2018 in “Trends in Immunology” This study demonstrated that antigens from the skin bacterium Staphylococcus epidermidis can stimulate CD8+ T cells, which in turn enhance wound healing.
September 2023 in “International Journal of Cosmetic Science” The researchers observed that two non-antimicrobial shampoos caused a significant increase in fungal germs but did not affect the overall scalp microbiota diversity over two weeks, suggesting these formulations may preserve or stimulate the scalp microbiota without adverse effects.
December 2021 in “Figshare” This study found that BBS7 is crucial for maintaining Shh signaling and periodontal ligament homeostasis, with occlusal hypofunction leading to its downregulation and impacting cell migration and angiogenesis.
April 2026 in “Open MIND” This case report suggests that Post-Finasteride Syndrome may involve a sustained imbalance in gut bacteria, with fermenting and hydrogen sulphide-producing bacteria disrupting hormone and mitochondrial functions.
15 citations
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June 2024 in “Frontiers in Pharmacology” This review examines drug repositioning as a strategy for combating bacterial infections, highlighting its potential to address multidrug-resistant strains and antibiotic resistance by analyzing safety profiles, synergistic combinations, and promising results for drugs initially used for other conditions.
December 2021 in “Figshare” This study found that BBS7 expression is crucial for maintaining Sonic hedgehog signaling activity and periodontal ligament homeostasis, suggesting its downregulation in occlusal hypofunction affects cell migration and angiogenesis.
18 citations
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November 2008 in “Disease-a-Month” This study developed a multifunctional injectable hydrogel that effectively provided hemostasis and accelerated healing of infected skin wounds, demonstrating significant potential for clinical wound dressing applications.
June 2024 in “Skin Research and Technology” In this study, researchers observed significant differences in microbial composition between UV-induced fluorescent and non-fluorescent scalp areas in patients with androgenetic alopecia, noting a higher abundance of Cutibacterium in the fluorescent regions.
1 citations
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January 1997 in “Proceedings of the British Society of Animal Science” This review addresses the role of biotin in animal metabolism, emphasizing the need for further research to understand its dietary and microbial sources in different developmental stages in pre-ruminant and mature ruminant animals, without reporting new experimental results.
June 2024 in “Journal of medical pharmaceutical and allied sciences” In this study, researchers observed that Pectin from Nagpuri oranges significantly increased colony counts of probiotic bacteria like L. acidophilus and L. plantarum both in vitro and in vivo, suggesting potential use as a prebiotic or synbiotic in nutraceutical formulations.
1 citations
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September 1993 in “Archives of Disease in Childhood” This article discusses the importance of considering biotinidase deficiency in differential diagnosis for patients with certain neurological and dermatological symptoms, as timely treatment with biotin is crucial to prevent severe consequences.
December 2021 in “Figshare” This study suggests that the downregulation of BBS7 in occlusal hypofunctional periodontal ligament impairs Shh signaling, which is essential for maintaining periodontal ligament homeostasis.