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This review discusses the role of the hedgehog signaling pathway in hematological cancers and its potential as a therapeutic target; it reports no new clinical findings.

This manuscript reviews the latest understanding of alopecia areata's pathogenesis, highlighting the roles of genetic, immunological, and environmental factors, with a focus on immune responses involving IFN-γ and cytotoxic CD8+ T-cells as key contributors to hair follicle inflammation and function disruption without follicle destruction.

This perspective reviews current knowledge about cellular and molecular mechanisms in wound healing from 2023–2025, highlighting inadequately understood pathways associated with conditions like keloids and chronic wounds, and discusses proposed novel therapies for these conditions.

This review discusses the therapeutic effects of vitamins, highlighting risks such as liver damage from prolonged high doses of vitamin A and hypercalcemia from excessive vitamin D, while noting a case of allergic reaction to vitamin B12.

UV radiation may cause DNA changes in skin, certain UVB therapy helps psoriasis, a new gene mutation is linked to mild piebaldism, different immune cells affect psoriasis, a drug promotes hair growth, and some cancer drugs could treat skin barrier issues.

This review discusses the synthesis and biological activities of jasmonates, highlighting their potential as drugs and prodrugs, but reports no new clinical results; further research and trials are anticipated.

This study introduces scINSIGHT, a method that showed improved performance over existing approaches in identifying gene expression patterns and cellular processes in heterogeneous scRNA-seq datasets from different biological conditions.

This study developed a carbohydrate chitosan-based biomaterial combined with a novel peptide to promote the chondrogenic differentiation of human adipose-derived stem cells, suggesting potential clinical applications for cartilage regeneration.

This meta-analysis of animal studies found that alkaloids have potential anti-influenza and anti-inflammatory effects, correlating with improved viral titers and survival rates, though they did not effectively reduce TNF-α and IL-6 levels. Extensive further studies are needed to confirm these findings before considering clinical application.

This case report describes a patient with an allergic sensitization to minoxidil, indicating that such patients should pursue alternative therapies to treat androgenetic alopecia.

Prasugrel is better than clopidogrel at preventing heart damage and improving blood flow in small heart vessels during heart artery procedures.

This article reviews the multifunctional roles of calreticulin outside the ER and highlights its impact on wound healing in animal models, but reports no new clinical results.

This article reviews the classification, pathogenesis, and treatment options for cutaneous lupus erythematosus and reports no new clinical findings.

This study found significant upregulation of IDO-1 and IDO-2 in human basal cell carcinomas, suggesting that IDO production may confer immune privilege characteristics to the tumors, potentially impacting their growth.

This study reports that permanent and severe alopecia is a newly identified complication of the FEC 100–docetaxel regimen used for adjuvant breast cancer treatment.

In this study, researchers found that the human hair follicle microbiota vary by anatomical compartment and donor age, with specific microbes like S. epidermidis potentially influencing hair follicle functions, which suggests new avenues for therapeutic targeting.

This case report illustrates the risk of skin necrosis in patients with high antiphospholipid antibody levels after stopping anticoagulation therapy, highlighting the necessity for careful monitoring.

This review discusses the potential use of essential oils and melatonin as nutraceuticals in dogs, highlighting their promising applications for addressing conditions like stress, anxiety, sleep disorders, and alopecia.

This review summarizes how genetic studies using conditional β-catenin loss- and gain-of-function mice have advanced understanding of canonical Wnt signaling's role in embryonic development, adult stem cell maintenance, and cancer modeling.

This review discusses the role of Toll-like receptors in wound healing and highlights their potential therapeutic value but notes that their role in human wound healing and chronic wounds is not well understood.

This study found that cutaneous pyridoxal 5'-phosphate hydrolase activity may be carried out by an enzyme different from the classical tissue-nonspecific alkaline phosphatase in human and mouse skin.

In this study, minoxidil was found to suppress the activity of normal human T-lymphocytes in vitro, though the physiological relevance of this effect remains uncertain.

In this experimental study, laser irradiation significantly altered the gene expression of cytokines in cultured human T-cell lymphocytes, suggesting that such laser light may photobiomodulate cytokine production in vitro.

This study found that the vitamin D receptor in lampreys, which lack bones and hair, binds 1,25-dihydroxyvitamin D3 and may function to induce enzymes for detoxifying substances.

This study found that mechlorethamine restored hair growth in mice with alopecia-areata-like disease by eliminating infiltrated lymphocytes and inhibiting certain pro-inflammatory cytokines in treated skin areas.

In this review, researchers discussed recent insights into caspases, enzymes initially associated with cell death and inflammation, revealing their broader roles in cell proliferation, migration, and differentiation, and highlighting the importance of caspase knock-out mice for understanding their implications in diseases.

The skin protects the body, regulates temperature, senses touch, and makes vitamin D.

Ets2 gene is crucial for placental development in mice.

This study found that the interaction between heat shock protein 90 and lamin A/C is crucial for the growth, migration, and self-aggregation of dermal papilla cells, suggesting a potential role in alopecia areata mechanisms.

This review addresses the role of skin-resident adult stem/progenitor cells in skin homeostasis, disease, and cancer development, and reports no new research results.