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      Testosterone Therapy for Transgender Men: Effects and Safety

      research Testosterone therapy for transgender men

      162 citations , April 2016 in “The Lancet Diabetes & Endocrinology”
      This review discusses the effects of testosterone therapy for transgender men, noting desired outcomes and potential risks, but reports no new research findings; the authors highlight a lack of high-quality data due to various study limitations.
      Lichen Planopilaris: Update on Diagnosis and Treatment

      research Lichen Planopilaris: Update on Diagnosis and Treatment

      160 citations , March 2009 in “Seminars in Cutaneous Medicine and Surgery”
      This article reviews lichen planopilaris, its presentation, and treatment challenges, and emphasizes the need for more research into its pathogenesis and therapy efficacy; it reports no new findings.
      The Hair Follicle as an Estrogen Target and Source

      research The Hair Follicle as an Estrogen Target and Source

      159 citations , July 2006 in “Endocrine Reviews”
      This article discusses the influence of estrogens on hair follicle growth and metabolism, suggesting a significant role alongside androgens in hair growth control but reports no new clinical results.
      Androgens and Human Hair Growth

      research Androgens and human hair growth

      157 citations , April 1994 in “Clinical endocrinology”
      Androgens can cause hair growth in some areas and hair loss on the scalp.
      Androgenetic Alopecia: A Review

      research Androgenetic alopecia: a review

      153 citations , March 2017 in “Endocrine”
      This review examines recent advances in understanding the pathophysiology and molecular mechanisms of androgenetic alopecia, highlighting two major genetic risk loci, but does not report new clinical findings.
      Gender Differences in Skin: A Review of the Literature

      research Gender differences in skin: A review of the literature

      152 citations , December 2007 in “Gender Medicine”
      This review discusses recent advances in understanding gender differences in skin and their implications for dermatologic diseases, but it reports no new experimental results; ongoing research is necessary for translating these insights into clinical practice.
      An Update on Congenital Adrenal Hyperplasia

      research An Update of Congenital Adrenal Hyperplasia

      151 citations , December 2004 in “Annals of the New York Academy of Sciences”
      This review discusses nonclassical 21-hydroxylase deficiency as the most common autosomal recessive disorder in humans and highlights the effectiveness of glucocorticoid treatment in reversing related symptoms.
      Drug-Induced Hair Loss and Hair Growth

      research Drug-Induced Hair Loss and Hair Growth

      147 citations , April 1994 in “Drug Safety”
      Some drugs can cause hair loss or increase hair growth, but these effects are usually reversible when the drug is stopped.
      Dermatological Adverse Events with Taxane Chemotherapy

      research Dermatological adverse events with taxane chemotherapy

      141 citations , September 2016 in “European Journal of Dermatology”
      This review examines dermatological side effects of taxane chemotherapy reported in past studies and highlights the necessity for identifying and managing these conditions to maintain cancer patients' quality of life; it presents no new clinical results.
      The Role of Vitamins and Minerals in Hair Loss: A Review

      research The Role of Vitamins and Minerals in Hair Loss: A Review

      134 citations , December 2018 in “Dermatology and Therapy”
      This review discusses the potential role of vitamins and minerals in managing non-scarring alopecia but reports no clinical results; the authors advocate for further controlled trials to explore these relationships.
      Electrolysis: Observations from 13 Years and 140,000 Hours of Experience

      research Electrolysis: Observations from 13 years and 140,000 hours of experience

      132 citations , October 1995 in “Journal of the American Academy of Dermatology”
      This report concludes that the blend method is the most effective electrolysis technique for permanent hair removal, requiring proper technique and preparation such as shaving before treatment to increase efficacy.
      Cells Within the Bulge Region of Mouse Hair Follicle Transiently Proliferate During Early Anagen: Heterogeneity and Functional Differences of Various Hair Cycles

      research Cells within the bulge region of mouse hair follicle transiently proliferate during early anagen: heterogeneity and functional differences of various hair cycles

      130 citations , January 1994 in “Differentiation”
      In this study, researchers found that bulge cells in mouse hair follicles undergo transient proliferation during early anagen, indicating their role as follicular stem cells. However, another factor beyond dermal papilla proximity may be required to initiate a new anagen phase.
      Hair Loss in Women

      research Hair Loss in Women

      129 citations , October 2007 in “The New England Journal of Medicine”
      This article discusses the evaluation and management of a 45-year-old woman with diffuse scalp-hair loss and reports no new clinical findings.
      Probiotic Bacteria Induce a Glow of Health

      research Probiotic Bacteria Induce a ‘Glow of Health’

      127 citations , January 2013 in “PLOS ONE”
      This study found that feeding aged mice a probiotic yogurt induced changes leading to thicker, healthier fur, suggesting a bacteria-triggered interleukin-10-dependent mechanism that mimics signs of youth and reproductive fitness.
      Isotretinoin Treatment of Acne and Related Disorders: An Update

      research Isotretinoin treatment of acne and related disorders: An update

      126 citations , October 1983 in “Journal of The American Academy of Dermatology”
      This report verifies isotretinoin's significant efficacy in treating severe acne over the past year in the U.S., highlighting the need for careful patient selection and monitoring due to potential side effects.
      Hair Regrowth

      research HAIR REGROWTH

      118 citations , April 1998 in “Dermatologic Clinics”
      This review discusses the advancements in understanding and treating androgenetic alopecia and alopecia areata but reports no clinical findings; the authors emphasize the need for further research on molecular control mechanisms.
      Atypical Progeroid Syndrome Due to Heterozygous Missense LMNA Mutations

      research Atypical Progeroid Syndrome due to Heterozygous Missense LMNA Mutations

      115 citations , October 2009 in “˜The œJournal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”
      In this study, researchers identified novel LMNA mutations in patients with atypical progeroid syndrome, revealing clinical features distinct from other similar disorders, but unrelated to mutant prelamin A accumulation.
      Genetic Basis of Skin Appendage Development

      research Genetic basis of skin appendage development

      111 citations , January 2007 in “Seminars in cell & developmental biology”
      This article reviews the similarities in early development processes of hair follicles, teeth, and mammary glands and reports no new experimental findings.
      Androgens and Androgen Receptor Action in Skin and Hair Follicles

      research Androgens and androgen receptor action in skin and hair follicles

      100 citations , September 2017 in “Molecular and Cellular Endocrinology”
      This review discusses the molecular mechanisms of androgens and androgen receptors in skin disorders, particularly androgenetic alopecia, and reports no new clinical results; it highlights potential areas for future treatment development.