January 2024 in “Wiadomości Lekarskie” This study reports that Abelson Interactor 1 (ABI1) regulates androgen receptor transcription in prostate cancer, identifying it as a potential target for new therapies addressing treatment resistance.
15 citations
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February 2013 in “Pharmaceutical nanotechnology” This study found that invasomes enhanced the iontophoretic transdermal delivery of finasteride in rabbits, increasing AUC and T1/2 compared to oral suspension.
7 citations
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January 2019 in “Australasian Journal of Dermatology” In this study, the CYP 21A2 gene p.V281L mutation was associated with an increased susceptibility to familial frontal fibrosing alopecia, suggesting an antigen-driven mechanism linked to certain human leukocyte antigen haplotypes.
67 citations
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October 2005 in “Annals of Oncology” This review found that fulvestrant is well tolerated in postmenopausal women with hormone receptor-positive advanced breast cancer, showing lower incidence of joint disorders than non-steroidal aromatase inhibitors.
47 citations
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May 1995 in “Journal of Investigative Dermatology” Hair follicles in people with alopecia have lower levels of a key blood vessel growth protein.
September 2021 in “Revista interdisciplinar em saúde” This study reported that oral isotretinoin effectively stabilized frontal fibrosing alopecia in patients, which may help guide healthcare providers in managing this condition related to hair loss and self-esteem.
September 2021 in “Revista Interdisciplinar em Saúde” In this observational study, treatment with oral isotretinoin was reported to stabilize hair loss in patients with frontal fibrosing alopecia, offering potential guidance for clinicians on its therapeutic use, with implications for improving affected patients' self-esteem.
29 citations
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January 2003 in “Dermatology” This study suggests a new subtype of alopecia, termed 'acute diffuse and total alopecia of the female scalp' (ADTAFS), characterized by acute and total hair loss in women with a favorable recovery profile.
January 2019 in “Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.)” This study found that the treatment group experienced a higher average increase in hair counts than the placebo group, but the difference was not statistically significant.
3 citations
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September 2021 in “EClinicalMedicine” In this study, ALRV5XR treatment significantly increased terminal hair density in men with androgenetic alopecia after 24 weeks, while also decreasing vellus hair density, and was well tolerated without adverse events, suggesting its potential efficacy over standard therapies.
August 2019 in “Journal of the American Academy of Dermatology” Frontal fibrosing alopecia may be caused by an autoimmune reaction and hormonal imbalance.
This study discusses a hypothesis that combining intermittent androgen ablation therapy with finasteride may enhance prostate cancer treatment, though new results from this approach are not yet available.
41 citations
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December 2008 in “Journal of the American Academy of Dermatology” This review discusses fixed drug eruption (FDE) potentially linked to finasteride and emphasizes dermatologists' need to recognize its possible occurrence due to the drug's widespread use, but reports no new clinical results.
1 citations
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October 2022 in “European medical journal” This summary reports that the 31st EADV Congress in Milan featured over 170 sessions with more than 600 speakers, offering dermatology and venereology professionals a platform to innovate practices and enhance patient care through global collaboration.
2 citations
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January 2016 in “Dermatology online journal” This case report describes a 46-year-old man diagnosed with frontal fibrosing alopecia, a condition primarily affecting postmenopausal women, highlighting its rare occurrence in men.
2 citations
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September 2019 in “Journal of the American Academy of Dermatology” USB videodermatoscopes are a practical and affordable alternative for diagnosing skin conditions.
September 2024 in “Journal of the American Academy of Dermatology” In this study, a novel compound named AH-001 demonstrated effective androgen receptor protein degradation, reducing hair loss progression in a mouse model of androgenetic alopecia, with minimal systemic exposure and side effects, suggesting potential for safer treatment.
September 2024 in “BMJ Case Reports” This case report highlights an atypical presentation of favus in an immunocompetent adult, where a psoriasiform plaque over the 'bindi' area was successfully treated with systemic itraconazole, achieving complete resolution without relapse. Simple stains proved essential for diagnosis in this resource-limited setting.
2 citations
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December 1997 in “Journal of The American Academy of Dermatology” The document concludes that doctors should monitor children's brain development when treating hemangiomas with interferon alfa and consider stopping the treatment if problems arise, while also exploring drugs that might counteract side effects.
June 2016 in “American Journal of Cardiology” This review discusses the preliminary results of using rotational thrombectomy for acute dialysis-access graft occlusion in the upper extremity, reporting no new clinical outcomes.
In this observational study, dutasteride treatment was associated with statistically significant stabilization of frontal fibrosing alopecia compared to other systemic therapies, with a dose-dependent effect observed across the frontal and bilateral temporal hairlines.
This research explores the integration of autologous regenerative therapy using adipose-derived stem cells and stromal vascular fraction in hair restoration surgery, aiming to improve follicular viability and enhance the environment around hair follicles, potentially offering benefits over traditional treatments like finasteride, minoxidil, and hair transplantation.
June 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that inhibiting the interaction between HOTAIR and EZH2 can block pro-fibrotic gene expression in fibroblasts and interfere with tissue remodeling in systemic sclerosis patient skin.
January 2024 in “Wiadomości Lekarskie” This review discusses the potential of augmented reality to advance vascular and endovascular surgery by improving 3D anatomical understanding and reducing patient risk, but notes that further research is needed to overcome current technological limitations.
July 2017 in “DOAJ (DOAJ: Directory of Open Access Journals)” In this patient series, researchers observed that subcutaneous scalp injections of adipose tissue enriched with stem cells showed potential as a safe and promising treatment for early genetic hair loss in men and women, based on photographic and quantitative assessments.
1 citations
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April 2023 in “Heliyon” In this study, a 68-year-old man with muscle-invasive bladder cancer and renal insufficiency achieved a partial radiological response to neoadjuvant therapy with gemcitabine and Disitamab Vedotin, without significant adverse events, highlighting a potential alternative for cisplatin-ineligible patients.
June 2025 in “British Journal of Dermatology” This study introduces ALUDWIG, an automated tool for assessing female androgenic alopecia severity from smartphone images, which may offer a more consistent alternative to current scoring methods like the Ludwig scale.
1 citations
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June 2025 in “Journal of Clinical Medicine” This study reported that frontal fibrosing alopecia predominantly affects postmenopausal women and identified potential risk factors like frequent β-blocker use and sunscreen application, indicating the need for further research.
339 citations
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February 2014 in “Journal of The American Academy of Dermatology” This study found that eyelash loss, facial papules, and body hair involvement were linked to severe frontal fibrosing alopecia, and antiandrogens were the most effective treatment.
1 citations
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March 2012 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” Dermoscopy helps diagnose frontal fibrosing alopecia by identifying specific scalp features.