Frontal Fibrosing Alopecia in a 46-Year-Old Man

January 2016 in “ Dermatology online journal ”

Forrest White, Shields Callahan, Randie H. Kim, Shane A Meehan, Jennifer Stein

frontal fibrosing alopecia scarring alopecia perifollicular erythema perivascular lymphocytic infiltrate periinfundibular fibrosis hormonally mediated

TLDR A 46-year-old man was diagnosed with frontal fibrosing alopecia, a condition usually seen in postmenopausal women.

Frontal fibrosing alopecia (FFA) is a scarring alopecia characterized by the recession of the frontotemporal hairline and often the loss of eyebrows, predominantly affecting postmenopausal women and rarely men. This case study reported a 46-year-old man with a 10-year history of an erythematous patch and perifollicular erythema at the superior forehead and frontotemporal hairline. A skin biopsy revealed a perivascular, lymphocytic infiltrate with periinfundibular fibrosis, confirming the diagnosis of FFA. The pathogenesis of FFA was poorly understood but might have been hormonally mediated.

View this study on escholarship.org →

Discuss this study in the Community →

Related Community Posts Join

6 / 377 results

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Interesting article links major MPB theories to western diet (and life-style)

in Research/Science 43 upvotes 1 day ago

community Fibrosing alopecia in a pattern distribution

in Research/Science 14 upvotes 7 months ago

A user has been experiencing hair loss for 4 years, with treatments like minoxidil, finasteride, and various supplements proving ineffective. They were diagnosed with fibrosing alopecia in a pattern distribution, a condition that may require a combination of anti-inflammatory and hair growth treatments.

community Actor Jacob Batalon, 26, has a receding hairline. I thought it was pretty cool to see a younger actor being successful, despite dealing with hair loss. His most well known role is Ned Leeds in the Marvel Cinematic Universe, and he is currently the CEO of Sex.

in Satire 498 upvotes 1 year ago

Actor Jacob Batalon's receding hairline and how it is a sign of his success despite dealing with hair loss, with some people suggesting he may be using treatments such as Minoxidil or Finasteride to manage it.

community I tried salt water to stop the DHT itch

in Treatment 60 upvotes 1 year ago

Treating the itch associated with male pattern baldness, which is believed to be caused by DHT. Potential treatments discussed include salt water, finasteride, ketoconazole, and RU58841.

community scarring alopecia awareness in this community

in Chat 33 upvotes 2 years ago

Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

Related Research

8 / 8 results

Bitemporal Scalp Hair Loss: Differential Diagnosis of Nonscarring and Scarring Conditions

research Hair Diseases

28 citations, September 1998 in “Medical Clinics of North America”

Most hair loss can be diagnosed with patient history and physical exam, and a few common types make up most cases.

research Evaluation of Hair Loss

21 citations, May 1996 in “Current problems in dermatology”

Detailed patient history and physical exams are crucial for diagnosing hair loss.

research Androgenetic Alopecia, Trichotrophic Substances, and Histologic Studies of the Human Scalp

5 citations, October 1988 in “Clinics in Dermatology”

Minoxidil promotes hair growth but exact mechanism is unknown.