Autologous Regenerative Therapy in Baldness Surgery

January 2025

Domenico Piccolo, Alessandro Gennai, Fabrizio Melfa, Bruno Bovani, Piero Tesauro

The chapter discusses the integration of Autologous Regenerative Therapy (ART) in hair restoration surgery, focusing on its potential to improve follicular viability and enhance the surrounding macroenvironment of hair follicles. It highlights the use of adipose-derived stem cells (ADSCs) and the stromal vascular fraction (SVF), which are obtained through minimally invasive fat harvesting techniques like guided SEFFI. This approach aims to address the limitations of traditional treatments like finasteride, minoxidil, and surgical hair transplantation by offering a more sustainable solution for androgenetic alopecia (AGA) through regenerative cellular components.

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229 citations , August 2002 in “Experimental Gerontology”

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.