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The interdigital gland of Vembur sheep shows sex-based differences in size and chemical makeup, possibly affecting communication and disease protection.

High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.

The circadian clock plays a key role in hair growth and its disruption can affect hair regeneration.

Different genes and pathways are active in yak skin and hair cells, affecting hair growth and immune responses.

Blocking specific proteins can help remove aging cells and might treat age-related diseases and promote hair growth.

Syndecan-1 is essential for maintaining skin fat and preventing cold stress.

SkQ1 antioxidant improved health and lifespan in mice.

Human stem cells can help form hair follicles in mice.

The review concluded that keeping the hair-growing ability of human dermal papilla cells is key for hair development and growth.

Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.

Epidermal growth factor helps stem cells heal wounds and regenerate hair follicles faster.

Removing Dicer from pigment cells in newborn mice causes early hair graying and changes in cell migration molecules.

Skin cell behavior is influenced by the tightness of nearby cells, affecting their growth and development.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Innate lymphoid cells help control skin bacteria by regulating sebaceous glands.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

Fibroblast state switching is crucial for skin healing and development.

Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.

A small group of slow-growing cells causes basal cell carcinoma to return after treatment.

Shift work disrupts the body's natural clock, leading to health problems.

Hormone treatment for transsexual individuals is effective but carries risks like thromboembolic events and mood changes, with most side effects being minor and reversible.

Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.

New therapies are being developed that target integrin pathways to treat various diseases.

Microneedle technology has advanced for painless drug delivery and sensitive detection but faces a gap between experimental use and clinical needs.

Aging slows wound healing due to weaker cells and immune response.

SIRT7 protein is crucial for starting hair growth in mice.

Ruxolitinib helps protect skin stem cells and keeps skin healthy in mice with skin GVHD.

Thymic mesenchymal cells have unique gene expression that supports their specific functions in the thymus.

The document concludes that a systematic approach is crucial to identify causes of androgen excess in women beyond the most common cause, Polycystic ovary syndrome (PCOS).