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research A Practical Guide to Hair Graft Placement Using the Sharp Implanter Method
This study explains surgical techniques for hair transplantation using the sharp implanter method, emphasizing 11 key principles that optimize efficiency and precision, and reports high graft survival and natural hair density when these principles are followed.
research Identification of Trichophyton rubrum by Nested PCR Analysis from Paraffin Embedded Specimen in Trichophytia Profunda Acuta of the Glabrous Skin
This case study identified Trichophyton rubrum as the cause of trichophytia profunda acuta in a patient using nested PCR, suggesting an alternative diagnostic approach when KOH tests and cultures fail.
research Unusual Presentation of Tinea Corporis Associated With the Use of a Microneedling Device
This case report describes a 26-year-old woman who developed an unusual fungal skin infection, possibly facilitated by using a microneedling device at home, highlighting the need for safer procedures and aftercare protocols to prevent infection.
research Bacteria induce skin regeneration via IL-1β signaling
This study found that skin microbiota, particularly in wild-type mice, promotes wound-induced hair follicle neogenesis and wound healing, highlighting the potential downsides of routine antibiotic use on skin regeneration.
research Serial cultivation of human scalp hair follicle keratinocytes
This study describes a method for serially cultivating adult human hair follicle keratinocytes using a specific growth substrate and cryogenic storage, enabling subculture and immunofluorescence studies.
research Design of an artificial skin. IV. Use of island graft to isolate organ regeneration from scar synthesis and other processes leading to skin wound closure
This study found that island grafting in guinea pigs enabled the isolated study of early skin regeneration processes, distinguishing them from natural wound closure mechanisms like epithelialization and contraction.
research Nanoparticle-Based Targeting of Vaccine Compounds to Skin Antigen-Presenting Cells By Hair Follicles and their Transport in Mice
In this study, transcutaneously applied nanoparticles and viral vectors were shown to penetrate murine hair follicles, internalize in antigen-presenting cells, and induce immune responses, suggesting a promising approach for vaccine delivery.
research Assessment of replication rates of human keratinocytes in engineered skin substitutes grafted to athymic mice
This study found that basal keratinocytes in engineered skin substitutes showed a proliferative phenotype and potential for long-term replication, which may enhance wound healing stability.
research An intrafamilial transmission ofArthroderma benhamiaein Canadian porcupines (Erethizon dorsatum) in a Japanese zoo
This study reported intra-familial transmission of Arthroderma benhamiae among Canadian porcupines in a Japanese zoo, with genetic sequences previously undocumented in Japan or the GenBank database.
research The evolution of healthy skin to acne lesions: a longitudinal, in vivo evaluation with reflectance confocal microscopy and optical coherence tomography
This study found that acne lesion formation involves early hyperkeratinization and inflammation around hair follicles, creating a self-sustaining cycle that may progressively worsen acne.
research Tata Laksana Onikomikosis Candida
This research reports that onychomycosis, a common nail fungal infection often caused by Candida yeast, requires laboratory testing like direct preparations, fungal cultures, and molecular tests for accurate diagnosis due to its diverse etiology and differential diagnosis, improving therapy effectiveness and efficiency.
research Autoimmunerkrankungen erfordern eine kombinierte Therapie aus Toleranzinduktion und Immunsuppression - Modelluntersuchung bei der Alopecia Areata
This study identified keratins as autoantigens in alopecia areata and found that a tolerogenic form of keratin application delayed disease progression in mice by affecting T-cell responses.
research Improved isolation of outer root sheath cells from human hair follicles and their proliferation behavior under serum-free condition
research A Simple In Vivo System for Studying Epithelialization, Hair Follicle Formation, and Invasion Using Primary Epidermal Cells from Wild-Type and Transgenic Ornithine Decarboxylase-Overexpressing Mouse Skin
This study demonstrated that the tracheal xenotransplant procedure is an effective technique for assessing the invasiveness of epidermal keratinocytes and studying factors affecting hair follicle formation.
research Learning Curve for the Hair Implanter Pen
This study evaluated the learning curve for using the Hair Implanter Pen, finding it to be operator dependent.
research [Hair follicle regeneration by injection of follicular cells].
This study reports that follicular cells isolated from murine skin can regenerate hair follicles after being injected into nude mouse skin, with the regeneration process relying on cell interactions, recipient sites, and cell numbers.
research Improved Method for the Isolation and Cultivation of Human Scalp Dermal Papilla Cells
research Efficacy of autogenic, allogenic and heterogenic platelet rich plasma (PRP) on Avulsion skin wounds in rabbit model
This study found that both autogenic and allogenic PRP therapies significantly improved wound contraction and healing in rabbits by day 15 and achieved complete wound closure by day 21, outperforming control and heterogenic PRP treatments.
research Microbial allies in skin trauma recovery: from immune modulation to engineered probiotic therapeutics
This review highlights recent advancements in engineered probiotics for wound healing, reporting that genetically engineered strains of Lactobacillus reuteri and Lactococcus cremoris have shown promise in promoting faster wound healing in pre-clinical and clinical settings, particularly for diabetic foot ulcers.
research [Growing of hair in alopecia areata & maligna after intracutaneous hydrocortisone injection].
research Observation on cadavers and through ultrasonography using a 2 mm needle length for intradermal injections
A 2 mm needle is effective and precise for skin injections.
research Development of Pneumatic Dual-Cell Stacking Implanter
This study developed a prototype pneumatic dual-cell implanter that successfully stacked and implanted cells in tests, reducing hand burden for operators, which may improve alopecia treatments compared to traditional hair transplantation.
research EFFICACY OF INTRALESIONAL BOTULINUM TOXIN INJECTION IN THE TREATMENT OF PATCHY ALOPECIA AREATA (AA)
In this randomized controlled trial, both Botulinum Toxin-A and Triamcinolone Acetonide showed substantial effectiveness in treating patchy Alopecia Areata, but Botulinum Toxin-A avoided complications while Triamcinolone led to skin atrophy in 16.7% of patients.
research An antimicrobial microneedle patch promotes functional healing of infected wounds through controlled release of adipose tissue-derived apoptotic vesicles
This study developed an antimicrobial microneedle patch for delivering apoptotic vesicles to treat infected wounds, which was found to effectively reduce bacterial growth and accelerate scarless healing, including the rapid formation of mature hair follicles in just 8 days, a previously unreported early outcome.
research Intranasal sensitization model of alopecia areata using pertussis toxin as adjuvant
This study proposes that intranasal exposure to PTx and autoantigen in an animal model can trigger autoimmune disease, supporting the idea that subclinical nasal colonization by BP may cause alopecia areata.
research 795 Bacteria induce skin regeneration
This study found that increasing commensal bacterial load on the skin enhances wound-induced hair follicle neogenesis in mice, mediated through IL1R-MyD88 signaling pathways.
research A volatile producing Bacillus subtilis strain from the rhizosphere of Haloxylon ammodendron promotes plant root development
This study found that volatile organic compounds from Bacillus subtilis strain WM13-24 enhanced root development in Arabidopsis and its host plant through auxin signaling.
research In vitroinvestigation of the follicular penetration of porcine ear skin using a nanoparticle-emulsion containing the antiseptic polihexanide
This study found that a curcumin-labeled particle-associated antiseptic penetrated deeper into hair follicles in porcine skin than particles without antiseptic.
research 281 Phase I/IIa clinical trial for the treatment of androgenetic alopecia using intradermal injections of cultured autologous dermal sheath cup cells
This study found that intradermal injections of cultured autologous dermal sheath cup cells for androgenetic alopecia showed hair loss stabilization at 24 months without serious adverse effects and a sustained response in some participants.