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Androgenetic alopecia, or hair loss, is caused by a mix of genetics, hormones, and environment, where testosterone affects hair growth and causes hair to become smaller and grow for a shorter time.

Testosterone increases heart and blood pressure issues in rats with endotoxemia, and stopping testosterone production can reduce these problems.

Sex steroids produced in the hippocampus are crucial for brain functions like memory and learning in rodents.

The study concluded that similar pathways regulate hair growth in dogs and mice, and these pathways are disrupted in dogs with Alopecia X, affecting stem cells and hormone metabolism.

Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.

Baicalin may help reduce excessive male hormone levels in PCOS.

Managing side effects of endocrine therapy is crucial to improve adherence and survival in breast cancer patients.

Hormones like testosterone and estrogen significantly affect hair growth and structure.

ESR2 gene variations may be linked to female pattern hair loss.

A new method can almost perfectly distinguish adenomyosis from similar conditions using blood tests.

Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Women with AGA have more androstenedione and dihydrotestosterone, less copper and zinc; copper imbalance affects AGA; treatment improves hormones and minerals.

ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.

Two gene variations, rs6493497 and rs7176005, may be linked to female hair loss in Chinese people.

Clomiphene citrate improves fertility in men taking finasteride for hair loss.

Using 5-alpha reductase inhibitors may lower the risk of breast cancer in females.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

Treatment with plasma rich in growth factors improved hair density and thickness for hair loss patients.

Natural 5AR inhibitors effectively improve mild to moderate hair loss in men.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Plant extracts effectively reduce hair loss and increase growth, offering a safe alternative treatment.

Androgens significantly affect female hair loss, and hormonal treatments may help.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

The conclusion is that androgenetic alopecia and senescent alopecia have unique gene changes, suggesting different causes and potential treatments for these hair loss types.

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.

AR gene not major factor in female hair loss; different from male hair loss.

Apoptosis contributes to hair loss in androgenetic alopecia.