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In this study, maslinic acid applied topically was observed to stimulate hair growth in mice comparably to minoxidil, primarily activating pathways like Wnt/β-catenin, and suggesting a link between hair growth and cilia activity.

This study found that sulforaphane may help alleviate hair loss by increasing hair count after 18 weeks of use and enhancing the expression of a DHT-degrading enzyme in cellular models.

This study found that mimosine dipeptide enantiomers inhibit melanogenesis and cyclooxygenase enzymes in B16F10 melanoma cells, suggesting potential for treating skin hyperpigmentation and inflammation.

This study observed that topical application of maslinic acid stimulated hair growth in mice comparably to minoxidil, possibly through the Wnt/β-catenin pathway and involving ciliary gene activity, highlighting increased levels of trichogenic gene expression and protein levels.

In this study, the bark extract of Albizia saponaria was analyzed for its metabolites and potential anti-alopecia effects, identifying several compounds with predicted affinities for proteins involved in hair loss pathways.

This study observed that N-palmitoylethanolamine (PEA) may relieve pain by enhancing de novo neurosteroid synthesis, evidenced by increased allopregnanolone levels and protein expression in pain models, dependent on PPAR-α.

This study found that stimulating the olfactory receptor OR2AT4 in human hair follicles with a synthetic sandalwood odorant promotes hair growth ex vivo by decreasing apoptosis and increasing IGF-1 production.

This study concluded that the anesthesia protocol using fentanyl, propofol, cisatracuria besylate, tranexamic acid, atropine, and metoclopramide resulted in the least pain during septoplasty.

This study found that 0.75% adenosine lotion significantly improved hair growth and thickness in Japanese women with female pattern hair loss compared to a placebo.

The research found that topical maslinic acid stimulates hair growth in mice, comparable to minoxidil, by inducing anagen phase acceleration and activating pathways such as Wnt/β-catenin, Notch, and MAPK; a potential link to cilia activity was also explored.

This Cochrane review reports that 5-alpha reductase inhibitors may slightly reduce urological symptoms and acute urinary retention risk compared to placebo, with a possible small reduction in surgical intervention need compared to alpha blockers.

This study suggests that targeting olfactory receptors in the lung epithelium might help treat odorant-induced asthma in cases without type 2 inflammation, as these receptors could play a role in airway sensitivity to smells.

Finasteride reduces pain in male rats and works better with testosterone.

This review examines the molecular mechanisms by which the proapoptotic protein ARTS inhibits tumorigenesis and discusses prospects for developing drugs that mimic its function, with no new experimental results reported.

This article presents the SH-1 molecule as a novel AR antagonist for androgenetic alopecia treatment, highlighting its tissue-specific action and potential for commercialization, but provides no new clinical results.

This study found that cromakalim and pinacidil significantly inhibited porcine detrusor muscle contractions, suggesting these ATP-sensitive potassium channel openers may have potential in treating certain bladder diseases.

In this study, researchers observed that aroma oil-enhanced scalp scaling significantly improved scalp conditions over 8 weeks, marked by increased water and oil content, reduced keratin and surface value, and higher satisfaction in hair-related outcomes compared to the control group.

This study found that Ocimum basilicum L. showed the highest 5α-reductase inhibitory activity among ten Thai plants, despite no correlation between enzyme inhibition and total phenolic content.

This study suggests that fusaric acid at nontoxic concentrations may activate signal transduction in plants which could aid in the plant-defense responses against Fusarium spp.

This invention reports piperazine derivatives as potent inhibitors of type 3 17β-hydroxysteroid dehydrogenase, suggesting potential therapeutic applications in treating prostate cancer, acne, and androgenic alopecia.

This study found that fruit extracts from certain Egyptian Sabal species demonstrated significant anti-androgenic activity and potential therapeutic effects against benign prostatic hyperplasia in rat models and cell lines.

This study observed that aromatase inhibitors caused hair loss in menopausal women with breast cancer, mimicking male pattern baldness rather than female androgenetic alopecia.

This study found that both finasteride and a new steroidal compound, PM-9, competitively inhibit the 5α-reductase enzyme in Penicillium crustosum broth.

In this review, the authors detailed various dermatologic adverse events associated with aromatase inhibitors in postmenopausal women and discussed strategies to potentially prevent these events, aiming to minimize interruptions in breast cancer treatment.

In laboratory tests, this study found that a novel natural composition targeting 5-alpha reductase and inflammatory pathways reduced disease-related markers in androgenetic alopecia and benign prostatic hyperplasia more effectively than finasteride.

This study found no significant differences in hair growth between two formulas of hair tonic from meniran extract, one with a menthol enhancer, despite variations in hair length and weight measurements.

This study reported that newly synthesized phenanthridin-3-one derivatives effectively inhibit human steroid 5-α-reductase.

This survey reported that essential oils are predominantly used by Algerian women for cosmetic and medical purposes, with applications ranging from skincare to treating respiratory illnesses and other conditions.

In this study, among postmenopausal women with female androgenetic alopecia, the combination of Pygeum africanum and Serenoa repens extracts at higher doses plus MSM significantly increased total hair growth and hair resistance compared to a lower dose formulation after 16 weeks.