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Researchers developed reliable models to predict how well certain compounds bind to androgen receptors, emphasizing the importance of atomic electronegativity.

A 12-year-old boy with PAIS successfully developed male characteristics using high-dose testosterone and anastrozole.

Androgens increase muscle mass by promoting myoblast growth through ornithine decarboxylase.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.

Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

The new anti-acne treatment HA-P5 effectively reduces acne by targeting two key receptors and avoids an enzyme that can hinder treatment.

Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.

Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.

The mouse model suggests male pattern baldness may be due to an enzyme increasing DHT and higher androgen receptor levels in hair follicles.

cp-asiAR may effectively treat androgenetic alopecia by promoting hair growth and reducing androgen receptor activity.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

Androgens can help prevent memory problems caused by apoE4.

Male pattern baldness involves hormones and cell signals affecting hair growth.

Insufficient androgen action in male fetuses can cause genital development issues due to genetic mutations or environmental chemicals.

Mouse genital development depends on male or female hormones for specific features.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

The study suggests that motor neurons created from stem cells of patients with spinal and bulbar muscular atrophy show signs of the disease, including changes in protein levels and cell functions.

Mice with human gene experienced hair loss when treated with DHT.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

The conclusion is that androgenetic alopecia and senescent alopecia have unique gene changes, suggesting different causes and potential treatments for these hair loss types.

Androgenetic alopecia is mainly caused by genetic factors and increased androgen activity, leading to hair follicle miniaturization.

The study found that women with hyperandrogenic PCOS have higher levels of AKT1 and AKT2 proteins in their cells, which may lead to cell dysfunction.

New genetic insights have improved understanding of hair loss, leading to a new test and treatments, but more research is needed on the test and laser comb effectiveness.

Hormones and genes affect hair growth and male baldness.