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Shorter CAG repeats in a specific gene may increase male hormone activity and symptoms like acne and excess hair in women with PCOS.

The protein ARA70/ELE1 is involved in male pattern baldness, and lower levels of its short form may lead to hair thinning.

Early balding at 40 increases prostate cancer risk.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Different human traits like skin color and hair type vary between populations due to genetic adaptations to the environment.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Oestrogens are key for bone growth during puberty in both boys and girls.

Sphynx cats are hairless and Devon Rex cats have curly hair due to specific genetic mutations.

DHT, a testosterone byproduct, causes male pattern baldness.

Men with Kennedy disease have less chance of hair loss.

Flutamide improves female hair loss when other treatments fail, but may cause liver toxicity.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

Adjuvants, diet changes, and laser therapy may improve male pattern hair loss.

Parthenolide promotes hair growth in mice and may influence pathways related to male pattern baldness.

Different scalp and hair disorders are more common in certain ethnic groups, with the most common being androgenetic alopecia, which is treated with medications like minoxidil and finasteride.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Hair loss needs more research for better treatments.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Oxidative stress affects hair loss in men with androgenetic alopecia.

Aromatase gene variation may increase female hair loss risk.

Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

Metformin has limited effectiveness for improving PCOS symptoms and lacks clear benefits, needing more research to confirm its efficacy.

Azathioprine's effectiveness and safety require careful monitoring and more research, especially regarding its use with corticosteroids and the role of TPMT status in patients.

Finger length ratios are not linked to the number of specific gene repeats affecting testosterone sensitivity.

The model suggests that scalp tension could lead to hair loss, with factors like blood vessel hardening, enlarged oil glands, and poor microcirculation also playing a role. It also hints at a possible link between skull shape and baldness pattern.

Hair loss involves immune responses, inflammation, and disrupted signaling pathways.