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Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

The research concluded that selection significantly shaped the genetic variation of the X chromosome, with certain regions affected by past selective events.

A TP63 gene mutation causes significant hair loss and mild skin, nail, and tooth abnormalities.

Alopecia in patients with epidermolysis bullosa varies in severity and is often caused by skin blistering or trauma.

The KRTAP11-1 gene promoter is crucial for specific expression in sheep wool cortex.

The research found that male pattern hair loss is mostly genetic and involves hair thinning due to hormonal effects and changes in gene expression.

Hidradenitis Suppurativa has genetic links, with certain gene mutations more common in patients and a third of cases having a family history.

Curcuma aeruginosa Roxb. may help treat hair loss by affecting specific biological pathways.

Mutations in mitochondrial DNA might significantly contribute to the development of Polycystic Ovarian Syndrome.

Forensic DNA Phenotyping accurately predicts physical traits and is used in investigations, but needs more diverse population data for confirmation.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

No single biomarker is reliable enough for diagnosing and assessing SLE.

Low-coverage sequencing is a cost-effective way to find genetic factors affecting rabbit wool traits.

Certain fats in the blood are linked to an increased risk of male pattern baldness.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Oxidative stress and immune dysfunction are linked to both Hashimoto's thyroiditis and polycystic ovary syndrome, with diet and specific treatments important for managing these conditions.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

KAP9.2 and Hoxc13 genes are important for cashmere growth and vary in activity during different stages.

Lipids are important for healthy hair, but their exact role is not fully understood and needs more research.

New topical treatment using spherical nucleic acids shows promise in reducing psoriasis inflammation.

Eating a lot of fat increases PKCβ and inflammation in skin fat cells, which affects skin and hair health.

Copper deficiency may cause hair loss, and treating it could involve nutrition and hormones.

Parthenolide promotes hair growth in mice and may influence pathways related to male pattern baldness.

Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.

The protein ARA70/ELE1 is involved in male pattern baldness, and lower levels of its short form may lead to hair thinning.

Adjuvants, diet changes, and laser therapy may improve male pattern hair loss.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.