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Parkinson's disease is linked to skin disorders and skin cells help in studying the disease.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Certain fats in the skin help control inflammation and health, and changing these fats through diet or supplements might treat skin inflammation.

R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.

RU58841, a nonsteroidal anti-androgen, showed potential as a topical treatment for hair loss, increasing hair density, thickness, and length without systemic side effects in Stumptailed Macaques.

The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.

A new compound effectively inhibits human 5α-reductase 1.

Increased PPARGC1α relates to hair thinning in common baldness.

Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.

Dexamethasone affects hair growth by altering levels of proteins that either promote or inhibit hair follicle growth.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

Using minoxidil on dogs can cause serious cardiovascular damage, including arterial injury and hemorrhagic lesions.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Metformin should be used for PCOS mainly in those with glucose intolerance, and has limited benefits for infertility or hirsutism.

Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

A cream with a specific hormone blocker increases hair growth in mice.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

Androgens affect bone and fat cell development differently based on the cells' embryonic origin.

The composition with carnitine, thioctic acid, and saw palmetto extract may effectively reduce inflammation in hair follicle cells.