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Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.

The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.

Wnt, Eda, and Shh pathways are crucial for different stages of sweat gland development in mice.

Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.

Some skin conditions may indicate metabolic syndrome, which could help with early detection and management of related health issues.

Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.

The document explains hair growth and shedding, factors affecting it, and methods to evaluate hair loss, emphasizing the importance of skin biopsy for diagnosis.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

Finasteride improves hidradenitis suppurativa but not for child-bearing women.

The document concludes that Nonclassic Congenital Adrenal Hyperplasia requires personalized treatment plans to manage symptoms and fertility, with glucocorticoids being a common therapy.

Ice-skating athletes often have skin problems due to cold, infections, and inflammation, needing careful treatment and prevention.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Pregnancy can cause normal skin changes that usually go away after childbirth and don't need treatment.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Seborrhea in Parkinson's disease may be linked to hormones, not autonomic impairment.

Vitiligo is not linked to coeliac disease, but a small number of alopecia areata patients may have it, suggesting they should be tested for coeliac disease.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

Non-classic congenital adrenal hyperplasia is a common disorder causing symptoms like acne and infertility, and it's managed based on symptoms, not just test results. Treatment can improve fertility and reduce miscarriage risk.

Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.

Most pregnant women experience skin darkening and hair changes, with these effects usually going away after giving birth.

Better hair care products are needed to protect against grooming and chemical damage.

The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.

Accurate clinical, histological, and genetic methods are key for understanding and treating hair disorders.

Sweat glands and hair follicles are structurally connected within a specific layer of skin fat.

New treatments for a chronic skin condition show promise, but individualized plans are crucial due to varying responses.

The skin is a complex barrier that protects the body, regulates temperature, and helps with immune responses.

Eccrine sweat gland's clear cells likely cause excessive sweating in hyperhidrosis.

Mice are useful for researching human hair loss and testing treatments, despite some differences between species.