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Topical oligonucleotide therapy targets hair follicles effectively.

Indian men have 62.1% hair loss, mostly grade II vertex, and less extensive than other populations.

Fat-related cells are important for initiating hair growth.

The research shows that a gene called Wnt3 affects hair growth and structure, causing short hair and balding when overactive.

Polymeric nanoparticles show promise for treating skin diseases.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Probiotic bacteria improved skin and hair health in aged mice.

Cystatin M/E strongly inhibits cathepsin V and cathepsin L, important for skin formation.

New methods have greatly improved our understanding of stem cell behavior and roles in the body.

Neurosteroids show promise for treating epilepsy and more research is needed.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Wnt10b makes hair follicles bigger, but DKK1 can reverse this effect.

Reduced AR gene methylation may cause early pubic hair growth in girls.

Bismuth subgallate and borneol together improve skin wound healing better than when used separately or compared to other treatments.

Iron deficiency may contribute to hair loss.

Pannexin 3 is important for bone formation and the development of bone cells.

The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.

Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

The protein ARA70/ELE1 is involved in male pattern baldness, and lower levels of its short form may lead to hair thinning.

The type 3 IP3 receptor is important for controlling hair loss and growth.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

The monkey's hair loss was due to an autoimmune disease, not genetics.

Antiandrogen therapy helps treat genetic hair loss.