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Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Mutations in certain receptors can cause diseases and offer new treatment options.

Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.

Hormonal antiandrogen therapy for acne is underused and can reduce the need for antibiotics.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

Dutasteride treatment in men with mild to moderate COVID-19 reduced viral shedding, inflammation, and recovery time without serious side effects.

Use antiandrogens and other treatments for hair loss.

New treatments targeting androgen receptors show promise for drug-resistant prostate cancer.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Female pattern hair loss diagnosed by scalp appearance, treated with combined therapies and targeted approaches.

Antiandrogens help manage PCOS symptoms but need careful monitoring.

New treatments for hair loss are being developed using molecular biology.

Possible new treatments for common hair loss include drugs, stem cells, and improved transplants.

New hair loss treatments may include topical medications, injections, and improved transplant methods.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.

PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

The trial will test if proxalutamide is safe and effective in reducing death in severe COVID-19 patients.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

Sex hormones affect reproduction, sexual development, and oral health, and it's important for dental practitioners to understand their effects and interactions.

Combination therapy with oral contraceptives and spironolactone improves hair growth, menstrual issues, and acne in women with PCOS.

Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.

The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.

A boy with a rare form of early puberty caused by a new gene mutation responded well to treatment aimed at reducing testosterone and preserving adult height.