Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review highlights the promising potential of microemulsions and nanoemulsions in (trans)dermal drug delivery, noting a gap in understanding their distinct mechanisms and composition-related effects on skin permeability, while emphasizing the limited clarity on mesostructures and cosolvent impacts.

This review discusses dietary manipulation strategies in a mouse model of CBS deficiency and reports no new results; the authors emphasize the importance of understanding gene-diet interactions.

This review discusses the potential therapeutic role of the edible plant Solanum nigrum for managing COVID-19 symptoms and post-COVID complications based on in silico docking and pharmacological studies, but reports no new clinical results.

This review explores the efficacy and safety of treatments for dissecting cellulitis of the scalp, revealing a predominance of case reports and series, and concludes that randomized controlled trials are needed for better evidence-based therapies.

People with cleft lip and palate often have respiratory problems.

This study found a direct correlation between chronic tonsillitis and increased NETosis activity in peripheral blood and palatine tonsil lacunae.

This study found that patients with RASopathies demonstrated lower levels of serum IgA and CD8 T cells compared to controls, potentially indicating an increased risk of developing autoimmune disorders.

This review examines recent advancements in electrospun nanofibers for wound healing applications, but reports no new experimental results, highlighting their potential in sutures, dressings, and skin regeneration.

This review examines the functions of vitamin D and its receptor in skin and explores how these are regulated, reporting no new clinical results.

This review discusses the conserved molecular mechanisms controlling hair follicle development and cycling and suggests they may also apply to other ectodermal derivatives, like teeth and feathers, but it reports no new results.

In this study of 20 patients with erosive pustular dermatosis of the scalp, using trichoscopy improved diagnosis, and treatments with high-potency steroids or topical tacrolimus effectively reduced inflammatory signs, suggesting these as first-line treatments.

This study found that taking a daily oral dose of 50mg DHEA for one year had no significant impact on blood lipids, insulin sensitivity, or the endometrium in postmenopausal women with low libido.

In this study, researchers found that deleting Caspase-9 in hair follicle stem cells delayed apoptosis, leading to accelerated wound repair and new hair follicle regeneration by maintaining apoptotic cells as signaling centers.

This study demonstrated that elevated glucocorticoid levels in transgenic mice led to pancreatic exocrine cells transforming into hepatocyte-like cells, resulting in pancreatic dysfunction.

This review discusses hair follicle stem cells for wound healing and reports no new clinical results, noting their potential but emphasizing the need for further understanding and safety in clinical applications.

This study found that over- and ectopic-expression of FoxN1 in early life negatively affected the development of thymic epithelial cells, T and B cells, and skin epithelial cells.

This study found that minicircle-based gene therapy significantly lowered total homocysteine levels and improved liver CBS activity in a mouse model of CBS deficiency.

This study observed that zinc deficiency in humans and mice was associated with diminished allergic contact dermatitis but increased severity and duration of irritant contact dermatitis.

This review summarizes the antioxidant and anticarcinogenic properties of Indian Gooseberry, its phytochemical composition, and its use in traditional Ayurvedic medicine, but reports no new clinical results.

The study highlights Teak's (Tectona grandis) diverse applications beyond high-quality timber, emphasizing its bioactive compounds' pharmacological potential in cancer treatment and other uses across traditional medicine, cosmetics, and biodiesel production.

This study observed a strong positive association between the expression of the p53 protein and the appearance of dark neurons in the hippocampus of rats following experimental septoplasty, suggesting p53's potential neuroprotective role alongside its activation of damaged neurons.

This review highlights the need for tailored hormonal treatment strategies for non-binary transgender individuals, emphasizing personalized care to enhance psychological well-being and quality of life.

This study highlights the underexplored allergenic potential of Trichophyton rubrum, a dermatophyte, which can trigger IgE-mediated allergic reactions and a Th2 immune response shift, underscoring the need for its inclusion in diagnostic panels and further research for treating chronic mycoses and related allergies.

This study found that differentiated airway epithelial cells can revert into functional stem cells in vivo, suggesting a more general role for this dedifferentiation process in tissue regeneration in higher vertebrates.

This review discusses melatonin's potential in dermatology, highlighting its antioxidative, immunomodulatory, and DNA repair properties, but reports no new clinical results.

This study suggests that melatonin plays a role in hair follicle function by modulating growth and pigmentation, and it may act as a protective agent in active hair growth phases.

This review discusses the potential of ultraviolet (UV) radiation technologies in wound care, highlighting their antimicrobial properties and risks of DNA damage, but reports no new clinical findings.

This article reviews current strategies and advancements in regenerating skin appendages and sensory nerves in tissue-engineered skin, highlighting the challenge of restoring skin sensations like pain, temperature, and touch to improve patients’ quality of life.

In this review, the researchers highlight LED therapy as an emerging and safe treatment for skin inflammatory conditions, aging, and hair growth disorders, noting its integration into dermatological practice but emphasizing the need for more controlled studies to confirm its efficacy.

This study found that midazolam improved PTSD-associated behavioral deficits in rats through its action on the TSPO, CBR, and neurosteroidogenesis pathways.