3 citations,
May 2023 in “Biomedicines” PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.
2 citations,
October 2022 in “Rheumato” A young woman with severe symptoms was diagnosed with SLE and improved significantly after treatment.
April 2024 in “Journal of clinical medicine” Recognizing specific skin features helps diagnose and manage lupus erythematosus effectively.
A patient with patchy hair loss was successfully treated for Tumid Lupus Erythematosus after other treatments failed.
41 citations,
August 1988 in “Journal of The American Academy of Dermatology” A woman with subacute cutaneous lupus erythematosus had widespread skin symptoms triggered by medication and sunlight, which improved with specific treatments.
March 2019 in “Journal of medical science and clinical research” Skin problems are common and early signs of Systemic Lupus Erythematosus, and certain immune system markers are important for diagnosis and treatment.
April 2018 in “Rheumatology” Alopecia is common in lupus patients, causing significant anxiety and is linked to the disease itself.
125 citations,
December 2016 in “Molecules” Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.
26 citations,
February 2016 in “Respiratory Medicine” Auto-antibody testing is a useful but not definitive tool in diagnosing interstitial lung diseases, and using a specific algorithm could make testing more cost-effective.
Many patients with cutaneous lupus erythematosus experience hair loss and nail problems, which are important for diagnosis and treatment.
49 citations,
October 2014 in “International Scholarly Research Notices” Eclipta alba has many health benefits and contains compounds with potential for drug development.
6 citations,
December 2022 in “Cell reports” Eating a high-fat fish oil diet caused mice to lose hair due to a specific immune cell activity in the skin linked to a protein called E-FABP.
March 2024 in “EMBO molecular medicine” Antiviral drugs, especially daclatasvir, may be a new treatment for a rare skin disease, improving survival and reducing symptoms in mice.
17 citations,
August 2001 in “Australasian journal of dermatology” A woman's liver problems improved after she stopped taking spironolactone.
3 citations,
March 2017 in “Case Reports in Dermatology” A woman with lupus improved significantly from scalp hair loss after treatment, highlighting the need to identify psoriatic alopecia in lupus patients to avoid permanent hair loss.
109 citations,
November 2004 in “Lupus” The paper concludes that the 1982 criteria for diagnosing systemic lupus erythematosus need updating to improve accuracy and involve dermatologists in the process.
32 citations,
December 2018 in “Cytokine” Type I interferons play a key role in the development of various skin diseases.
31 citations,
April 2016 in “Nature communications” Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.
23 citations,
April 2018 in “Journal der Deutschen Dermatologischen Gesellschaft” Permanent hair loss from cicatricial alopecia is treated by reducing inflammation and managing symptoms, but regrowth in scarred areas is unlikely.
6 citations,
January 2014 in “American Journal of Medical Case Reports” Early diagnosis, intensive therapy, and careful follow-up are crucial for managing overlapping TTP and SLE.
147 citations,
November 2020 in “International Journal of Molecular Sciences” Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.
130 citations,
September 2018 in “Cell Reports” Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.
65 citations,
July 2006 in “Journal of biological chemistry/The Journal of biological chemistry” The gene Foxq1, controlled by Hoxc13, is crucial for hair follicle differentiation.
62 citations,
November 2009 in “Aging Cell” Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.
59 citations,
June 2022 in “Frontiers in medicine” There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.
51 citations,
September 2020 in “Cell Metabolism” Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.
47 citations,
December 2019 in “Frontiers in immunology” A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.
47 citations,
January 2019 in “Nature communications” Polyamines help fix DNA damage accurately in cells.
41 citations,
July 2017 in “Journal of The American Academy of Dermatology” Men with Frontal fibrosing alopecia typically lose hair on the front scalp and sometimes on sideburns and upper lip, with treatments showing varied success.
40 citations,
March 2019 in “Nature Communications” CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.