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The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Trilostane effectively and safely treats dogs with pituitary-dependent hyperadrenocorticism, improving symptoms and adrenal gland size.

Four-amino acid part makes enzyme sensitive to finasteride.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

New genes and pathways are important for testosterone production and male sexual development.

Finasteride reduces hairiness and androgen levels in women with unexplained excessive hair growth.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.

Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.

Women with PCOS often have more body hair, acne, and skin darkening, and these signs are linked to metabolic issues like insulin resistance and high cholesterol.

Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.

The document concludes that hair transplantation and gene therapy may be important for future hair loss treatment.

Antiandrogen treatments combined with oral contraceptives can help manage hair growth and hair loss in women with PCOS.

Low-dose finasteride effectively treats hirsutism, is safe, and cost-effective.

Men with male-pattern baldness have more androgen receptors in their scalp's oil glands, which may contribute to hair loss.

Spironolactone improved blood vessel function and cholesterol levels in non-obese women with PCOS.

There's no significant link between the D19S884 marker at the insulin receptor gene and polycystic ovary syndrome.

Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.

Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

Finasteride 5 mg/day effectively treats hair loss in postmenopausal women without hyper-androgenism.

Excessive hair growth can be assessed by history, exam, and blood tests, and treated with medication like dexamethasone, birth control pills, and spironolactone.

Shorter CAG repeats in a specific gene may increase male hormone activity and symptoms like acne and excess hair in women with PCOS.