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New compounds were made and tested, with compound 6 showing potential for treating prostate-related diseases.

Androgens, male hormones, affect physical and mental functions, with a decrease leading to health issues like muscle loss, bone disease, and depression, and more research is needed on long-term effects and treatments.

Saw palmetto extract may help with hair loss and acne but needs more research on safety and long-term effects.

Taking 1 mg finasteride for a year reduces dihydrotestosterone levels in men with early hair loss, but doesn't change their metabolic state.

DHT in the human prostate is produced through multiple pathways, not just from testosterone.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

DHEA affects various tissues by interacting with multiple receptors and can be converted into sex hormones.

Testosterone can slow hair growth in adult monkeys, but a blocker called RU 58841 can counteract this and potentially help hair regrow.

Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

Cimicifuga racemosa extract may help prevent and treat prostate issues by inhibiting 5α-reductase.

Sons of mothers with polycystic ovary syndrome (PCOS) have a higher risk of obesity and insulin resistance, possibly due to certain genes and factors passed down from their mothers.

Blocking androgen activity in newborn rats affects body weight and appetite-related hormones differently in males and females.

Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might reduce it. AST decreases recurrence-free survival but doesn't affect overall survival or progression-free survival. More research is needed to understand AST's benefits.

Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might decrease the risk. AST also lessens the chance of cancer coming back but doesn't really affect survival rates. More research is needed to understand AST's benefits for different bladder cancers.

Allopregnanolone can reduce gut inflammation and normalize neurotransmitter levels after finasteride withdrawal.

Finasteride may cause lasting sexual and mental health issues, and genetic screening could help prevent them.

A specific metabolite, not a receptor protein, triggers the production of certain kidney enzymes, but this process is disrupted in mice with a mutation causing testicular feminization.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

Human beard hair follicles change testosterone into other related hormones, but don't much change androstenedione into testosterone.

Blocking a specific enzyme in male rat fetuses leads to the development of nipples and feminized genitalia.

Thujae occidentalis semen extract may help treat male pattern baldness by blocking a hair loss-related enzyme and reducing hair loss in mice.

Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.

Finasteride safely lowers DHT levels without affecting testosterone.

Flutamide may slightly improve hair loss in women, but finasteride does not work.

Aldactone was more effective in reducing hair growth in women with hirsutism than Diane, despite having less impact on hormone levels.

Method accurately measures finasteride in human plasma.

Spironolactone can reduce hair growth and testosterone in hirsutism, but is less effective than combined treatments.

Birth control pills can help reduce mild to moderate acne in women.