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Polycystic Ovary Syndrome (PCOS) affects 6%-15% of women of reproductive age, causing symptoms like acne and hair loss, and increasing the risk of type 2 diabetes and heart disease; it's managed through diet, exercise, and medications like Metformin and hormonal contraceptives.

Non-daily contraceptives cause fewer side effects and are more satisfying to women, and certain oral contraceptives can treat acne and seborrhoea, with a combination of chlormadinone acetate and ethinyl estradiol being highly effective and safe.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Hidradenitis suppurativa improves with antiandrogen therapy.

Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.

Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.

A teenage girl with high androgen levels and PCOS developed a rare liver tumor, suggesting a possible link between high androgens and the tumor's growth.

The T-zone on the face has more androgen receptors and produces more oil than the U-zone.

Androgen receptors in the mouse brain may explain cognitive and mood changes in prostate cancer treatment.

PrEP doesn't increase STI risk in high-risk men, anti-androgen drugs may lower ICU admission for male COVID-19 patients, a 3-point injection is better for crow's feet, and the 'Geriatric-8' tool could help assess frailty in older skin cancer patients.

The over-the-counter supplement DHEA could make COVID-19 worse, especially in diabetics and people with G6PD deficiency.

Higher androgen levels during puberty are linked to shorter adult height in boys with Silver-Russell syndrome.

Women with hyperandrogenism have higher androgen levels and lower SHBG, which may contribute to conditions like excessive hair growth and early puberty.

A boy's early puberty caused by a testicular tumor returned to normal after surgery.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

Sebaceous glands in our skin, developing during pregnancy and active in puberty, produce sebum for skin lubrication, temperature control, and fighting germs, also help in hormone regulation, and their dysfunction can cause conditions like acne and hair loss.

Hair loss improved after removing pituitary tumor.

Androgenetic alopecia is a long-term, immune-related disorder that starts during puberty due to androgen secretion, and it might be improved with iron tablets, platelet transfusion, and anti-inflammation therapy.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.

Young women with diffuse hair loss may have low SHBG levels, which could lead to more active testosterone and contribute to their hair loss.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Men are more likely to have severe respiratory viral infections like COVID-19 due to hormonal and genetic differences, while women generally have stronger immune responses.

Spironolactone might cause painful intercourse and decreased sexual arousal in women.

Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.

Most women with excessive hair growth have PCOS; treatment varies and focuses on preventing new hair, with electrolysis as the only permanent removal method.

Testosterone therapy can improve sexual function in women but long-term safety is unclear.

Cell transplantation faces challenges in genitourinary reconstruction, but alternative tissue sources and microencapsulation show promise.

Certain gene variations are linked to a higher risk of severe acne, suggesting a genetic influence on the condition.