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Diphenyl ethers can potentially reduce excess oil production when applied on the skin, helping treat conditions like acne.

CB-03-01 is a promising skin cream for treating hormone-related skin problems without causing harmful body-wide effects.

Pfizer found that pantolactam-based compounds can reduce sebum (skin oil) production when applied topically.

Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.

The authors maintain that shorter androgen receptor alleles may lead to milder COVID-19 by positively affecting the immune response, not due to changes in testosterone levels or activity.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

Shorter CAG repeats may cause hair and skin issues, while longer ones may link to acne.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

Androgens increase a growth factor in hair cells by creating reactive oxygen species, and antioxidants might help treat hair loss.

Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.

Hidradenitis suppurativa improves with antiandrogen therapy.

Dietary changes, including weight loss and a balanced diet, are important for managing PCOS, especially in overweight women.

New compounds with carborane showed anti-androgen effects similar to flutamide.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Mutations in certain receptors can cause diseases and offer new treatment options.

Red deer only have androgen receptors in neck hair cells for mane growth during breeding season.

Blocking the FGF5 gene in sheep leads to more fine wool and active hair follicles due to changes in certain cell signaling pathways.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.