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Finasteride in male rats causes liver and metabolic issues in their offspring.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Men with coeliac disease may have hormone imbalances that could affect sexual function, but these can improve with better gut health.

Asian hair loss differs from Europeans; consider individual needs and psychological well-being for treatment.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

Hormonal male contraception is effective and could be market-ready, but more research is needed to ensure safety for all ethnic groups.

Group a wide range of chemicals, not just phthalates, for assessing risks to male reproductive health.

Hirsutism is excessive male-pattern hair growth in women, often caused by hormonal imbalances, and requires ongoing treatment to manage.

Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.

Acne severity in women with PCOS is linked to younger age, lower body weight, and more body hair, but not to hormone levels.

Treatments for common hair loss include minoxidil, finasteride, and hair transplantation.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

Treating hirsutism in women often requires a mix of medications and cosmetic methods for best results.

Effective treatments for spinal and bulbar muscular atrophy are not yet available; more research is needed.

The conclusion is that young women with excessive hair growth should be quickly tested for hormonal issues and treated to improve their social well-being.

Testosterone therapy can modestly improve sexual function in menopausal women but should be used cautiously and is not recommended for routine measurement in sexual dysfunction or hirsutism.

Spironolactone might cause painful intercourse and decreased sexual arousal in women.

Hirsutism in women often indicates a hormonal imbalance and can be managed with a combination of hormonal treatments and hair removal methods.

COVID-19 may affect male fertility and women might have better outcomes due to hormonal and immune differences.

Hirsutism causes significant psychological distress in women.

Men with male pattern baldness have a higher risk of aggressive prostate cancer and benign prostatic hyperplasia.