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TGF-β1 from dermal papilla cells suppresses hair growth, and targeting it may help treat androgenetic alopecia.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Hair follicle size is mainly influenced by the number of cells and extracellular matrix volume, with cell number having a larger impact.

The mouse model suggests male pattern baldness may be due to an enzyme increasing DHT and higher androgen receptor levels in hair follicles.

High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.

Treatments for common hair loss include minoxidil, finasteride, and hair transplantation.

Hair loss from genetics and hormones can be treated with drugs or surgery.

Ovarian steroid cell tumors should be considered in adults with hirsutism and high testosterone, with surgery as the main treatment.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Balding hair follicle cells are smaller, grow less well, and need more effort to culture than non-balding cells.

Human hair follicle cells can grow hair when put into mouse skin if they stay in contact with mouse cells.

Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.

Rubus coreanum may help hair growth but not through the tested mechanisms, and none of the herbal extracts help with acne.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.

After menopause, some women lose scalp hair and gain facial hair, with patterns suggesting different underlying causes.

Finasteride increases hair count and improves hair growth with low risk of side effects.

Increased PPARGC1α relates to hair thinning in common baldness.

Baldness in men with prostate cancer is linked to higher levels of certain sex hormones, but chest hair density is not.

Animal models, especially mice, are essential for advancing hair loss research and treatment.

Animal models are crucial for learning about hair loss and finding treatments.

Hair from balding and non-balding areas regrows similarly on mice.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Dexamethasone increases the activity of androgen receptors in human skin cells, which may link it to certain types of hair loss.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.

A new treatment called SAMiRNA-AR68 increases hair count in people with hair loss, showing similar results to existing treatments but without side effects.

The study suggests that a specific gene variation and higher gene activity are linked to increased baldness in Egyptian men.

The LncRNA AC010789.1 slows down hair loss by promoting hair follicle growth and interacting with miR-21 and the Wnt/β-catenin pathway.