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Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

Testosterone can slow down hair growth when combined with certain cells from bald scalps, and this effect can be blocked by an androgen receptor blocker.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

Most women with excessive hair growth have PCOS; treatment varies and focuses on preventing new hair, with electrolysis as the only permanent removal method.

The treatment effectively promotes hair regrowth in androgenetic alopecia without causing skin irritation.

Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.

The document explains how male reproductive hormones work and affect the body.

Testosterone can slow hair growth in adult monkeys, but a blocker called RU 58841 can counteract this and potentially help hair regrow.

Adipose-derived stem cells may help with hair loss, but more research is needed.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

A drug called cimetidine can help treat hair loss in women by blocking androgen receptors. However, it's not the first choice and needs more research.

Finasteride, a hair loss drug, may cause long-term sexual side effects due to changes in hormone receptor levels.

Androgens play a key role in hair growth and disorders like baldness and excessive hairiness.

Baldness, especially at the front, may lower the risk of testicular cancer by 31%, but its link to prostate cancer is unclear.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

The research found that male pattern hair loss is mostly genetic and involves hair thinning due to hormonal effects and changes in gene expression.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

Hair loss needs more research for better treatments.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

Androgens slow hair growth by altering Wnt signaling in balding cells.

Cyanidin 3-O-arabinoside may help treat a common form of hair loss by protecting cells against aging and improving cell function.

Noni fruit extract, specifically the FEA-3 sub-fraction, can increase hair growth and reduce baldness in male rabbits, potentially acting like common hair loss treatments.

Only minoxidil and finasteride are FDA-approved for hair loss, with other treatments available but less effective or with side effects.

Skin problems in PCOS, like excess hair, acne, and hair loss, may not always indicate high male hormone levels and need careful diagnosis for proper treatment.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Hair follicle size is mainly influenced by the number of cells and extracellular matrix volume, with cell number having a larger impact.

Ustekinumab significantly improved sexual function and quality of life for people with moderate to severe psoriasis.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

ERG increases SOX9, promoting prostate cancer growth and invasion.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.