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Oral contraceptives lower testosterone levels in women, especially those with certain genetic traits, and may be linked to increased breast cancer risk.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.

Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.

Dutasteride and finasteride affect different cell types differently.

Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.

Testosterone replacement therapy improved blood sugar and fat levels without raising prostate cancer risk in Japanese men with low testosterone.

CB-03-01 is a promising skin cream for treating hormone-related skin problems without causing harmful body-wide effects.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

Androgens may worsen COVID-19 and hair loss could indicate the disease's severity.

Metformin improves early signs of heart disease in women with PCOS and raises apelin levels, but doesn't significantly change artery thickness.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Finasteride does not prevent bladder cancer.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Testosterone replacement therapy improves libido, mood, muscle strength, and bone density in men with Testosterone Deficiency Syndrome.

Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.

ERG increases SOX9, promoting prostate cancer growth and invasion.

A new compound, 3a, effectively fights prostate cancer better than finasteride.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

The same hormone can affect gene expression differently in various tissues, which could lead to new treatments for conditions like hair loss.

Prostate cancer patients need early psychological and sexual support during radiotherapy to improve their quality of life.

Androgen treatment with dihydrotestosterone may help maintain height in patients with 5-α-reductase type 2 deficiency, especially before puberty.

Men with male pattern baldness may be more at risk for severe COVID-19, and anti-androgen treatments could offer protection.

5-Alpha reductase inhibitors may prevent prostate cancer but are not widely used due to concerns about trial relevance and potential risks, and more research is needed to confirm long-term benefits.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Finasteride helps treat prostate issues and may prevent prostate cancer in high-risk men.

Don't combine abiraterone and spironolactone for prostate cancer treatment as it may worsen the disease.

5α-reductase inhibitors don't stop bladder cancer from developing or getting worse.