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Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Finasteride effectively treats BPH but may increase sexual dysfunction risk.

Spironolactone is a safe and effective treatment for reducing excessive hair growth in women.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

Flutamide combined with an LHRH agonist effectively inhibits prostate growth, suggesting it could treat prostate cancer.

The normal human prostate does not significantly affect blood DHT levels.

Metformin works better for adolescent girls with PCOS who have certain genetic variations.

RU58841 significantly increases hair growth rate and initiates more hair cycles, but doesn't affect hair thickness, suggesting it could be a new treatment for baldness.

Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.

Nandrolone and oxandrolone could help treat male health issues like muscle loss and low testosterone.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Flutamide is more effective and has fewer side effects than spironolactone for treating hirsutism.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Men with coeliac disease may have hormone imbalances that could affect sexual function, but these can improve with better gut health.

Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.

Spironolactone helps regrow hair in women with hair loss.

DHEA did not improve sexual function, well-being, or menopausal symptoms in postmenopausal women with low libido but caused side effects like acne and increased facial hair.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

Group a wide range of chemicals, not just phthalates, for assessing risks to male reproductive health.