research Effect of 5α-Dihydrotestosterone and Testosterone on Apoptosis in Human Dermal Papilla Cells
High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.
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120-150 / 1000+ results research Intracrine and Myotrophic Roles of 5α-Reductase and Androgens
Muscles can make their own androgens, which may help muscle growth.
research Bioengineered Polyester Nanoparticles for the Synergistic Treatment of Androgenic Alopecia via the Suppression of 5α-Reductase and Knockdown of Androgen Receptor
Bioengineered nanoparticles can effectively treat hair loss by targeting specific enzymes and receptors.
research Antiandrogen Therapy in Dermatology
Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.
research Androgen Effects in Mammals
Testosterone is crucial for development, growth, and various body functions in mammals.
research Molecular Genetic and Endocrine Mechanisms of Hair Growth
Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.
research Visualizing Androgen Receptor Activity in Male and Female Mice
Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.
research Disorders Linked to Insufficient Androgen Action in Male Children
Male children's genital development issues can be caused by genetic mutations or environmental factors affecting hormone action.
research Female Hirsutism: Pathophysiological Considerations and Therapeutic Implications
Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.
research Early-Onset Androgenetic Alopecia and Endocrine Disruptors
Endocrine disruptors may cause early hair loss.
research Androgen Replacement Therapy in Women
Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.
research Disorders Linked to Insufficient Androgen Action in Male Children
Insufficient androgen action in male fetuses can cause genital development issues due to genetic mutations or environmental chemicals.
research Anti-Alopecia Activity of Coumarin Derivatives from Merremia Peltata Leaves and Their Binding to Androgen Receptors: A Molecular Study
Scopolin and scopoletin from Merremia peltata leaves may help treat hair loss and showed promising results in rabbit tests.
research DHT and E2 Synthesis-Related Proteins and Receptors Expression in Male Yak Skin During Different Hair Follicle Stages
Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.
research The Mechanisms of Anabolic Steroids, Selective Androgen Receptor Modulators, and Myostatin Inhibitors
Anabolic steroids boost muscle growth, SARMs increase muscle mass and bone density without side effects, and myostatin inhibitors block a protein that stops muscle growth, but each has potential risks.
research Is Dehydroepiandrosterone a Hormone?
Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.
research Testosterone Therapy in Men: Clinical and Pharmacological Perspectives
Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.
research The Role of Dexamethasone in Mediating the Contradictory Effects of Wnt Antagonists SFRP2 and SFRP3 on Human Hair Follicle Growth
Dexamethasone affects hair growth by altering levels of proteins that either promote or inhibit hair follicle growth.
research Procyanidin Oligomers Selectively and Intensively Promote Proliferation of Mouse Hair Epithelial Cells In Vitro and Activate Hair Follicle Growth In Vivo
Procyanidin compounds from grape seeds were found to significantly increase mouse hair growth.
research Advances in Male Hormone Substitution Therapy
New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.
research Adrenal Steroid Precursors Exert Potent Androgenic Action in the Hamster Sebaceous Glands of Flank Organs and Ears
Certain adrenal hormones can strongly stimulate oil gland growth in hamster skin, similar to male hormones.
research Regulation of Masculinization: Androgen Signaling for External Genitalia Development
Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.
research Structure of Human Type II 5 Alpha-Reductase Gene
The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.
research Immuno-Endocrinology of COVID-19: The Key Role of Sex Hormones
Sex hormones may affect COVID-19 severity, with estrogen possibly reducing risk and testosterone potentially increasing it.
research Rooster Feathering, Androgenic Alopecia, And Hormone-Dependent Tumor Growth: What Is In Common?
Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.
research Effectiveness of Exosome Treatment in Androgenetic Alopecia: Outcomes of a Prospective Study
Exosome treatment safely increases hair density in male patients with androgenetic alopecia.
research The 5alpha-Reductase Type 1, But Not Type 2, Gene Is Expressed in Anagen Hairs Plucked from the Vertex Area of the Scalp of Hirsute Women and Normal Individuals
The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.
research Pre-Receptor Regulation of the Androgen Receptor
Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.
research Androgens and Androgen Receptor in the Management of Skin Diseases
Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.
research Applications of Exosomal miRNAs from Mesenchymal Stem Cells as Skin Boosters
Exosomal miRNAs from stem cells can help improve skin health and delay aging.