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Male hormones worsen kidney transplant damage, but blocking them helps.

Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.

Certain genetic variations in the SHBG gene are linked to an increased or decreased risk of PCOS in Mediterranean women.

Testosterone therapy seems safe for short-term use in postmenopausal women with low sexual desire, but more research on long-term effects is needed.

Acne treatment varies, with topical and systemic therapies effective, and more research needed on treatment order and long-term effects.

Lifestyle changes like diet and exercise are key for treating overweight women with polycystic ovary syndrome.

Obese women had more testosterone and less acne, but similar hair growth compared to non-obese women.

Early treatment and lifestyle changes are important for managing PCOS in young people to prevent long-term health issues.

Aldactone effectively reduces hair thickness in women with excessive hair growth, both alone and with other treatments.

A woman's severe hormone imbalance after menopause led to finding a rare ovarian tumor, treated by surgery.

Taking DHEA for a year is generally safe for postmenopausal women but may cause acne and more facial hair without improving metabolism or aging.

The document concludes that managing PCOS involves treating symptoms, regulating periods, and reducing health risks, with specific medications for fertility and metabolic issues.

A combination of nanomilled oral testosterone and dutasteride normalized testosterone levels in men with low testosterone and is safe for short-term use.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Allopregnanolone changes gene expression in glioblastoma cells.

Finasteride and flutamide effectively reduce hirsutism in PCOS women, with flutamide also lowering hormone levels.

Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.

The conclusion is that metformin is a first-line treatment for PCOS, particularly for restoring ovulation and increasing pregnancy rates, with other treatments depending on specific symptoms.

Testosterone therapy may improve mood, well-being, and sexual function in premenopausal women, but more research is needed on its long-term safety and effectiveness.

Taking low-dose spironolactone and metformin together works better for PCOS symptoms than either drug alone.

Certain drugs that block specific enzymes can help treat prostate diseases.

A transwoman developed a brain tumor after nine years of hormone therapy, suggesting a possible link between the treatment and tumor development.

A new gene variant causes glucocorticoid resistance in a mother and son.

Newer low-dose oral contraceptives with less androgenic effects improve patient compliance.

Cytochrome P-450 enzymes in the skin help break down various substances and could be targeted to treat skin conditions.

Laser treatment effectively increases hair density and thickness in androgenic alopecia.

The review concludes that more research is needed to better improve the health outcomes for people with Polycystic Ovarian Syndrome.

Long-term use of a certain medication can worsen erectile function in aged rats by damaging penile muscle cells.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Covers common skin issues in kids, their diagnosis, treatment, and need for specialist care.