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Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

The androgen receptor's shape-changing ability helps it function but can lead to cancer treatment resistance.

Hormones, nutrition, and seasonal changes regulate hair growth cycles, with androgens extending growth phases and factors like aging and malnutrition affecting hair loss and thinning.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Liquorice may reduce testosterone and affect male reproductive organs, potentially helping treat conditions like prostate cancer.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

Researchers developed reliable models to predict how well certain compounds bind to androgen receptors, emphasizing the importance of atomic electronegativity.

Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.

Androgens slow hair growth by altering Wnt signaling in balding cells.

Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Cells from balding scalps have more androgen receptors than cells from non-balding scalps.

Too much male hormone is the main cause of Polycystic Ovary Syndrome.

E211 G>A gene linked to lower risk of severe prostate cancer and hair loss.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

Androgen conjugates might be better indicators of skin sensitivity to hormones in women with excessive hair growth.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.

Scutellaria baicalensis extract and baicalin may help prevent hair loss.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Mutations in certain receptors can cause diseases and offer new treatment options.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.

Dutasteride and finasteride affect different cell types differently.