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Reduced androgens linked to kinky hair disorder and hair loss; 5a-reductase inhibitors may help.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Different stem cells are key for hair growth and health, and understanding their regulation could help treat hair loss.

Melatonin applied to the scalp helps increase hair density in people with early hair loss.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Oestrogens are key for bone growth during puberty in both boys and girls.

Vitamin D receptor binds similarly to natural and synthetic ligands, affecting gene regulation.

Dihydrotestosterone (DHT) doesn't affect rat skin cell growth, but it does change cell cycle, protein levels, and other cell functions, potentially shortening hair growth cycle.

AMT may cause hair loss and changing dWAT activity could help treat it.

Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.

Minocycline may cause hair loss by increasing DHT levels, but finasteride can help counteract this effect.

The document concludes that managing PCOS involves treating symptoms, regulating periods, and reducing health risks, with specific medications for fertility and metabolic issues.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.

Finasteride has a higher risk of reproductive side effects than minoxidil.

Dihydrotestosterone affects hair growth by changing the Wnt/β-catenin pathway, with low levels helping and high levels hindering growth.

Colchicine can inhibit hair growth by affecting cell activity and protein expression in hair follicles.

DHT affects hair follicle cells by changing microRNA levels, leading to less cell growth and more cell death.

Barn owls with smaller black spots have higher testosterone levels, which might be due to genetic effects on hormone regulation rather than hormone effects on coloration.

DHT affects testicular development and regulates spermatogenesis in some fish.

Free Testosterone Index, bioavailable testosterone, and androstenedione are the most accurate for diagnosing excess male hormones in PCOS.

Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.

Chinese medicine may help treat hair loss by affecting genes and enzyme activity.

A woman with low thyroid function did not lose her hair during chemotherapy, possibly because her hair follicles were less affected by the treatment.

Flutamide-induced hypospadias in rats slows down early wound healing.

Human scalp hair follicles have PGE2 and its receptors, which might affect hair growth.

Hair follicle biology advancements may lead to better hair growth disorder treatments.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.

Androgens, like testosterone, are crucial for early testicular descent in rats.