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Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

Testosterone helps beard and axillary hair cells grow by releasing growth factors from dermal papilla cells.

A 15-year-old girl with no menstrual period was diagnosed with a genetic condition that makes her body unable to respond to male hormones, leading to female characteristics despite having male genetic makeup.

E211 G>A gene linked to lower risk of severe prostate cancer and hair loss.

A new method helps detect androgen receptor movement in cells, aiding research on hair loss treatments.

The length of CAG repeats in the androgen receptor gene is linked to ovarian reserve but does not affect how the ovaries respond to stimulation.

TGF-β1 increases androgen receptor activity in hair loss, but Hic-5/ARA55 can counter this effect.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

The document concludes that accurate diagnosis and treatment are crucial in dermatology, and it presents various findings on skin conditions and treatments.

Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

Testosterone can both promote hair growth and cause baldness by affecting hair growth signals.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Longer CAG repeat lengths in the androgen receptor gene are linked to higher testosterone levels in women with PCOS.

Scientists found new nonsteroidal compounds that can act like natural male hormones and might help treat male fertility and hormone issues.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

Men have worse COVID-19 outcomes than women due to genetic and hormonal differences.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

ERG increases SOX9, promoting prostate cancer growth and invasion.

Breast cancer treatments work better with AR activation, improving results and reducing side effects.

Finasteride may improve prostate cancer treatment outcomes.

Certain genes and X chromosome patterns may significantly contribute to the development of hair loss.

Mutations at Val-889 and Arg-752 disrupt key interactions in the androgen receptor, affecting its function.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Testosterone works in different ways, including direct interaction with its receptor, conversion to other hormones for specific effects on genitalia, hair, bones, and muscle, and changes in body fat and sexual function when low.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

A certain gene variant may increase the risk of polycystic ovary syndrome in Chinese women.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.